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Literature summary extracted from

  • Abe, K.; Ohno, Y.; Sassa, T.; Taguchi, R.; Caliskan, M.; Ober, C.; Kihara, A.
    Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile (2013), J. Biol. Chem., 288, 36741-36749.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.38 expressed in Saccharomyces cerevisiae Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.3.1.38 P182L the mutant exhibits lower trans-2-enoyl-CoA reductase activity as compared with the wild type enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.38 trans-2-enoyl-CoA + NADPH + H+ Homo sapiens
-
 acyl-CoA + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.38 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.38 HEK-293T cell
-
 Homo sapiens
-
1.3.1.38 HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.38 trans-2-enoyl-CoA + NADPH + H+
-
 Homo sapiens acyl-CoA + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.38 NADPH-dependent trans-2-enoyl-CoA reductase
-
 Homo sapiens
1.3.1.38 TER
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.38 NADPH
-
 Homo sapiens