Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Widemann, E.; Miesch, L.; Lugan, R.; Holder, E.; Heinrich, C.; Aubert, Y.; Miesch, M.; Pinot, F.; Heitz, T.
    The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves (2013), J. Biol. Chem., 288, 31701-31714.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.127 expression in Escherichia coli Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.127 indole-3-acetic-acid-L-alanine + H2O Arabidopsis thaliana
-
 indole-3-acetic-acid + L-alanine
-
 ?
3.5.1.127 jasmonoyl-L-isoleucine + H2O Arabidopsis thaliana
-
 jasmonic acid + L-isoleucine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.127 Arabidopsis thaliana
-
-
-
3.5.1.127 Arabidopsis thaliana Q8VYX0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.127 12-hydroxyjasmonoyl-L-isoleucine + H2O
-
 Arabidopsis thaliana 12-hydroxyjasmonic acid + L-isoleucine
-
 ?
3.5.1.127 indole-3-acetic-acid-L-alanine + H2O
-
 Arabidopsis thaliana indole-3-acetic-acid + L-alanine
-
 ?
3.5.1.127 jasmonoyl-L-isoleucine + H2O
-
 Arabidopsis thaliana jasmonic acid + L-isoleucine
-
 ?
3.5.1.127 jasmonoyl-L-isoleucine + H2O 9fold higher activity than with 12-hydroxyjasmonoyl-L-isoleucine Arabidopsis thaliana jasmonic acid + L-isoleucine
-
 ?
3.5.1.127 additional information no substrates: 12-hydroxyjasmonoyl-L-isoleucine, 12-carboxyjasmonoyl-L-isoleucine Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.127 IAA-amino acid hydrolase ILR1-like 6
-
 Arabidopsis thaliana
3.5.1.127 IAR3
-
 Arabidopsis thaliana
3.5.1.127 ILL6
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
3.5.1.127 Arabidopsis thaliana rapid and transient induction upon wounding up

General Information

EC Number General Information Comment Organism
3.5.1.127 physiological function amidohydrolases IAR3 and ILL6 define a second pathway for jasmonoyl-L-isoleucine turnover during the wound response in Arabidopsis thaliana leaves. The two enzymes cleave the jasmonoyl-L-isoleucine signal, but act also on the tuberonic acid-isoleucine conjugate. The abundant accumulation of tuberonic acid (12-hydroxyjasmonic acid) after wounding originates partly through a sequential pathway involving conjugation of jasmopnic acid to isoleucine, oxidation of the jasmonoyl-L-isoleucine conjugate, and cleavage under the action of the amidohydrolases Arabidopsis thaliana