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Literature summary extracted from

  • Sirakova, T.D.; Dubey, V.S.; Cynamon, M.H.; Kolattukudy, P.E.
    Attenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesis (2003), J. Bacteriol., 185, 2999-3008.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.261 Mycobacterium tuberculosis P96285
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2.3.1.261 Mycobacterium tuberculosis H37Rv P96285
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Synonyms

EC Number Synonyms Comment Organism
2.3.1.261 msl7
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 Mycobacterium tuberculosis
2.3.1.261 PKS1
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 Mycobacterium tuberculosis
2.3.1.261 Pks15
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 Mycobacterium tuberculosis

General Information

EC Number General Information Comment Organism
2.3.1.261 physiological function a gene disruption mutant is not able to produce dimycocerosyl phthiocerol, although it can produce mycocerosic acids. The mutant is attenuated in a murine model, supporting the hypothesis that dimycocerosyl phthiocerol is a virulence factor Mycobacterium tuberculosis