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Literature summary extracted from
- Correlation between dihydropyrimidine dehydrogenase and efficacy and toxicity of fluoropyrimidine drugs (2014), Eur. Rev. Med. Pharmacol. Sci., 18, 2772-2776.
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.3.1.2 | 150000 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.1.2 | 5,6-dihydrouracil + NADP+ | Homo sapiens | - |
uracil + NADPH + H+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.1.2 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.1.2 | blood | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.1.2 | 5,6-dihydrouracil + NADP+ | - |
Homo sapiens | uracil + NADPH + H+ | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.3.1.2 | DPD | - |
Homo sapiens |
| 1.3.1.2 | DPYD | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.1.2 | FAD | - |
Homo sapiens | |
| 1.3.1.2 | NADP+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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