BRENDA - Enzyme Database

Characterization of two mitochondrial flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenases in Trypanosoma brucei

Skodova, I.; Verner, Z.; Bringaud, F.; Fabian, P.; Lukes, J.; Horvatha, A.; Eukaryot. Cell 12, 1664-1673 (2013)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.1.5.3
mitochondrion
-
Trypanosoma brucei
5739
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.5.3
sn-glycerol 3-phosphate + a quinone
Trypanosoma brucei
-
glycerone phosphate + a quinol
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
Trypanosoma brucei 29-13
-
glycerone phosphate + a quinol
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.5.3
Trypanosoma brucei
-
-
-
1.1.5.3
Trypanosoma brucei 29-13
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.5.3
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
740404
Trypanosoma brucei
dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
-
-
?
1.1.5.3
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
740404
Trypanosoma brucei 29-13
dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
-
740404
Trypanosoma brucei
glycerone phosphate + a quinol
-
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
-
740404
Trypanosoma brucei 29-13
glycerone phosphate + a quinol
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.5.3
FAD
-
Trypanosoma brucei
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.5.3
FAD
-
Trypanosoma brucei
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.1.5.3
mitochondrion
-
Trypanosoma brucei
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.5.3
sn-glycerol 3-phosphate + a quinone
Trypanosoma brucei
-
glycerone phosphate + a quinol
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
Trypanosoma brucei 29-13
-
glycerone phosphate + a quinol
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.5.3
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
740404
Trypanosoma brucei
dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
-
-
?
1.1.5.3
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
740404
Trypanosoma brucei 29-13
dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
-
740404
Trypanosoma brucei
glycerone phosphate + a quinol
-
-
-
?
1.1.5.3
sn-glycerol 3-phosphate + a quinone
-
740404
Trypanosoma brucei 29-13
glycerone phosphate + a quinol
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
1.1.5.3
physiological function
isoform mtG3PDH is essential for the bloodstream stage of Trypanosoma brucei, while in the procyclic stage the enzyme is dispensable
Trypanosoma brucei
General Information (protein specific)
EC Number
General Information
Commentary
Organism
1.1.5.3
physiological function
isoform mtG3PDH is essential for the bloodstream stage of Trypanosoma brucei, while in the procyclic stage the enzyme is dispensable
Trypanosoma brucei