EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.9 | 1-butyl-5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-butyl-5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-butyl-5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-cyclopropyl-5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-cyclopropyl-5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-cyclopropyl-5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 1-cyclopropyl-5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,3-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,4-dimethylphenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2,6-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2-chloro-3-nitrophenoxy)-1-cyclopropyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2-chloro-3-nitrophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2-chloro-3-nitrophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(2-methyl-3-nitrophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-1-cyclopropyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(1E)-3-methylbut-1-en-1-yl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(1E)-pent-1-en-1-yl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(1H-pyrrol-2-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(furan-2-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(thiophen-2-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(thiophen-3-yl)ethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | 5-(4-chlorophenoxy)-2-(methoxymethyl)-4H-pyran-4-one | - |
Staphylococcus aureus | |
1.3.1.9 | isoniazid | - |
Staphylococcus aureus | |
1.3.1.9 | linezolid | - |
Staphylococcus aureus | |
1.3.1.9 | triclosan | - |
Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.9 | Staphylococcus aureus | - |
- |
- |
1.3.1.9 | Staphylococcus aureus MRSA | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.9 | trans-2-octenoyl N-acetylcysteamine + NADH + H+ | - |
Staphylococcus aureus | ? | - |
? | |
1.3.1.9 | trans-2-octenoyl N-acetylcysteamine + NADH + H+ | - |
Staphylococcus aureus MRSA | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.1.9 | enoyl-ACP reductase | - |
Staphylococcus aureus |
1.3.1.9 | enoyl-acyl carrier protein reductase | - |
Staphylococcus aureus |
1.3.1.9 | FabI | - |
Staphylococcus aureus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.9 | NADH | - |
Staphylococcus aureus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.3.1.9 | 0.00008 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00011 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00012 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00022 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00038 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.0004 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00044 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | triclosan | |
1.3.1.9 | 0.00045 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00047 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-1-cyclopropyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00048 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-cyclopropyl-5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00063 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-butyl-5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00065 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | |
1.3.1.9 | 0.00066 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2-chloro-3-nitrophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00068 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00072 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-1-methyl-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00084 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.001 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-butyl-5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00114 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00125 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00125 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-butyl-5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00142 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00142 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | |
1.3.1.9 | 0.0015 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-cyclopropyl-5-(2,3-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00182 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00189 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00204 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00229 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00245 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00269 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)-1-phenylpyridin-4(1H)-one | |
1.3.1.9 | 0.00294 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00312 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(thiophen-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00317 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-cyclopropyl-5-(2,4-dimethylphenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00344 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00348 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00352 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2-methyl-3-nitrophenoxy)-2-(phenoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00374 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00389 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(furan-2-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00412 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00453 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00457 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(thiophen-2-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00479 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00488 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00498 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.0052 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chlorophenoxy)-2-(methoxymethyl)-4H-pyran-4-one | |
1.3.1.9 | 0.00533 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,4-dimethylphenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00568 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-2-[(E)-2-(furan-3-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00578 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(1E)-3-methylbut-1-en-1-yl]-4H-pyran-4-one | |
1.3.1.9 | 0.00582 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(E)-2-(1H-pyrrol-2-yl)ethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.00643 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 1-cyclopropyl-5-(2,6-dichlorophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.00644 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(4-chloro-2-methylphenoxy)-2-[(1E)-pent-1-en-1-yl]-4H-pyran-4-one | |
1.3.1.9 | 0.00673 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2,3-dichlorophenoxy)-2-[(E)-2-phenylethenyl]-4H-pyran-4-one | |
1.3.1.9 | 0.01173 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2-chloro-3-nitrophenoxy)-2-(phenoxymethyl)pyridin-4(1H)-one | |
1.3.1.9 | 0.01764 | - |
at pH 6.5 and 30°C | Staphylococcus aureus | 5-(2-chloro-3-nitrophenoxy)-1-cyclopropyl-2-(phenoxymethyl)pyridin-4(1H)-one |