BRENDA - Enzyme Database show

Substrate specificity and inhibitor sensitivity of rabbit 20alpha-hydroxysteroid dehydrogenase

Endo, S.; Arai, Y.; Hara, A.; Kitade, Y.; Bunai, Y.; El-Kabbani, O.; Matsunaga, T.; Biol. Pharm. Bull. 36, 1514-1518 (2013)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.1.1.149
expressed in Escherichia coli BL21(DE3) cells
Oryctolagus cuniculus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.149
3',3'',5',5''-tetrabromophenolphthalein
-
Oryctolagus cuniculus
1.1.1.149
benzbromarone
-
Oryctolagus cuniculus
1.1.1.149
Flufenamic acid
-
Oryctolagus cuniculus
1.1.1.149
galangin
-
Oryctolagus cuniculus
1.1.1.149
Hexestrol
-
Oryctolagus cuniculus
1.1.1.149
kaempferol
potent and competitive inhibitor
Oryctolagus cuniculus
1.1.1.149
Mefenamic acid
-
Oryctolagus cuniculus
1.1.1.149
myricetin
-
Oryctolagus cuniculus
1.1.1.149
naringenin
-
Oryctolagus cuniculus
1.1.1.149
Phenolphthalein
-
Oryctolagus cuniculus
1.1.1.149
quercetin
potent and competitive inhibitor
Oryctolagus cuniculus
1.1.1.149
Sulfobromophthalein
-
Oryctolagus cuniculus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.0005
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0006
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0006
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0008
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0009
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0011
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0012
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0013
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0013
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0014
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0017
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0018
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.002
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0022
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0022
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0025
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0026
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0028
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0029
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0031
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0034
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0041
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0042
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0042
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0053
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0055
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0057
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0059
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0059
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.006
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.006
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0062
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0062
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0067
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0074
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0076
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0078
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0089
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.011
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.013
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.014
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.019
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.034
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.053
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.061
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.068
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.088
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.111
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.131
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.152
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.162
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.18
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.26
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.4
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.149
Oryctolagus cuniculus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
1.1.1.149
Sepharose 6FF resin column chromatography
Oryctolagus cuniculus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.149
ovary
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.149
(S)-1-indanol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
(S)-1-tetralol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
17beta-estradiol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
2-tert-butyl-1,4-benzoquinone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
20alpha-hydroxyprogesterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
3-deoxyglucosone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-androstene-3,17-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-chromanol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-hydroxy-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-nitroacetophenone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-oxo-2-hexenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-oxo-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-pregnen-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5-androstene-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3alpha,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3alpha-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3beta-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-dihydrotestosterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-dihydrotestosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
5beta-pregnan-3,20-dione + NADPH + H+
-
-
-
r
1.1.1.149
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3,20-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha,20alpha-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha,21-diol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-17beta-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3alpha,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3alpha-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3beta-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3,20-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
-
-
r
1.1.1.149
5beta-pregnan-3alpha,20alpha-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3alpha,21-diol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
7alpha-hydroxy-dehydroepiandrosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
acetoin + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
acrolein + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
all-trans-retinal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
alpha-tetralone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
befunolol + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
beta-ionol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
dehydroepiandrosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
dehydroepiandrosterone 3-sulfate + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
diacetyl + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
estrone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
estrone 3-sulfate + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
geraniol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
hexanal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
isatin + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
isocaproaldehyde + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
ketotifen + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
menadione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
methylglyoxal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
additional information
no activity with 5beta-androstan-17beta-ol-3-one, 5beta-pregnan-20alpha-ol-3-one, testosterone and 20alpha-hydroxy progesterone
740126
Oryctolagus cuniculus
?
-
-
-
-
1.1.1.149
nonanal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
progesterone + NADPH + H+
-
740126
Oryctolagus cuniculus
20alpha-hydroxyprogesterone + NADP+
-
-
-
?
1.1.1.149
pyridine 3-aldehyde + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
testosterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-2-hexenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-benzene dihydrodiol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.0085
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.009
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.011
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0115
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.017
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.017
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.02
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.02
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.023
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.027
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.028
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.03
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.033
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.033
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.035
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.045
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.047
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.048
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.053
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.057
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.067
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.068
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.077
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.08
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.083
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.085
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.097
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.098
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.1
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.108
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.117
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.12
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.125
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.132
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.137
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.153
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.153
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.155
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.158
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.158
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.167
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.183
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.183
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.2
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.217
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.233
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.25
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.27
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.283
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.149
NADH
-
Oryctolagus cuniculus
1.1.1.149
NADPH
-
Oryctolagus cuniculus
IC50 Value
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
1.1.1.149
0.000022
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Phenolphthalein
1.1.1.149
0.000059
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
quercetin
1.1.1.149
0.00011
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
kaempferol
1.1.1.149
0.00012
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
benzbromarone
1.1.1.149
0.00037
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
naringenin
1.1.1.149
0.00041
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
galangin
1.1.1.149
0.00064
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
myricetin
1.1.1.149
0.003
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
3',3'',5',5''-tetrabromophenolphthalein
1.1.1.149
0.0064
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Hexestrol
1.1.1.149
0.01
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Mefenamic acid
1.1.1.149
0.011
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Sulfobromophthalein
1.1.1.149
0.026
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Flufenamic acid
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.149
expressed in Escherichia coli BL21(DE3) cells
Oryctolagus cuniculus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.149
NADH
-
Oryctolagus cuniculus
1.1.1.149
NADPH
-
Oryctolagus cuniculus
IC50 Value (protein specific)
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
1.1.1.149
0.000022
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Phenolphthalein
1.1.1.149
0.000059
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
quercetin
1.1.1.149
0.00011
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
kaempferol
1.1.1.149
0.00012
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
benzbromarone
1.1.1.149
0.00037
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
naringenin
1.1.1.149
0.00041
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
galangin
1.1.1.149
0.00064
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
myricetin
1.1.1.149
0.003
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
3',3'',5',5''-tetrabromophenolphthalein
1.1.1.149
0.0064
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Hexestrol
1.1.1.149
0.01
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Mefenamic acid
1.1.1.149
0.011
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Sulfobromophthalein
1.1.1.149
0.026
-
at pH 7.4 and 37°C
Oryctolagus cuniculus
Flufenamic acid
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.149
3',3'',5',5''-tetrabromophenolphthalein
-
Oryctolagus cuniculus
1.1.1.149
benzbromarone
-
Oryctolagus cuniculus
1.1.1.149
Flufenamic acid
-
Oryctolagus cuniculus
1.1.1.149
galangin
-
Oryctolagus cuniculus
1.1.1.149
Hexestrol
-
Oryctolagus cuniculus
1.1.1.149
kaempferol
potent and competitive inhibitor
Oryctolagus cuniculus
1.1.1.149
Mefenamic acid
-
Oryctolagus cuniculus
1.1.1.149
myricetin
-
Oryctolagus cuniculus
1.1.1.149
naringenin
-
Oryctolagus cuniculus
1.1.1.149
Phenolphthalein
-
Oryctolagus cuniculus
1.1.1.149
quercetin
potent and competitive inhibitor
Oryctolagus cuniculus
1.1.1.149
Sulfobromophthalein
-
Oryctolagus cuniculus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.0005
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0006
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0006
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0008
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0009
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.001
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0011
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0012
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0013
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0013
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0014
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0017
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0018
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.002
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0022
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0022
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0025
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0026
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0028
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0029
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0031
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0034
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0041
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0042
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0042
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0053
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0055
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0057
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0059
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0059
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.006
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.006
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0062
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0062
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0067
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0074
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0076
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0078
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0089
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.011
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.013
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.014
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.019
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.034
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.053
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.061
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.068
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.088
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.111
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.131
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.152
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.162
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.18
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.26
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.4
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.149
Sepharose 6FF resin column chromatography
Oryctolagus cuniculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.149
ovary
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.149
(S)-1-indanol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
(S)-1-tetralol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
17beta-estradiol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
2-tert-butyl-1,4-benzoquinone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
20alpha-hydroxyprogesterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
3-deoxyglucosone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-androstene-3,17-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-chromanol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-hydroxy-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-nitroacetophenone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-oxo-2-hexenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-oxo-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
4-pregnen-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5-androstene-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3alpha,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3alpha-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-androstan-3beta-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-dihydrotestosterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-dihydrotestosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
5beta-pregnan-3,20-dione + NADPH + H+
-
-
-
r
1.1.1.149
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3,20-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha,20alpha-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha,21-diol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5alpha-pregnan-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-17beta-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3alpha,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3alpha-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3beta,17beta-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-androstan-3beta-ol-17-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-20alpha-ol-3-one + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3,20-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
-
-
r
1.1.1.149
5beta-pregnan-3alpha,20alpha-diol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3alpha,21-diol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
5beta-pregnan-3alpha-ol-20-one + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
7alpha-hydroxy-dehydroepiandrosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
acetoin + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
acrolein + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
all-trans-retinal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
alpha-tetralone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
befunolol + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
beta-ionol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
dehydroepiandrosterone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
dehydroepiandrosterone 3-sulfate + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
diacetyl + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
estrone + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
estrone 3-sulfate + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
geraniol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
hexanal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
isatin + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
isocaproaldehyde + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
ketotifen + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
menadione + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
methylglyoxal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
additional information
no activity with 5beta-androstan-17beta-ol-3-one, 5beta-pregnan-20alpha-ol-3-one, testosterone and 20alpha-hydroxy progesterone
740126
Oryctolagus cuniculus
?
-
-
-
-
1.1.1.149
nonanal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
progesterone + NADPH + H+
-
740126
Oryctolagus cuniculus
20alpha-hydroxyprogesterone + NADP+
-
-
-
?
1.1.1.149
pyridine 3-aldehyde + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
testosterone + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-2-hexenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-2-nonenal + NADPH + H+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
1.1.1.149
trans-benzene dihydrodiol + NADP+
-
740126
Oryctolagus cuniculus
?
-
-
-
?
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.0085
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.009
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.011
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.0115
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.017
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.017
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.018
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.02
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.02
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.023
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.025
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.027
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.028
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.03
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.032
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.033
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.033
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.035
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.043
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.045
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.047
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.048
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.053
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.057
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.067
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.068
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.077
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.08
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.083
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.085
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.097
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.098
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.1
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.108
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.112
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.117
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.12
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.125
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.132
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.137
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.153
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.153
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.155
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.158
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.158
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.167
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.183
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.183
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.2
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.217
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.233
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.25
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.27
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.283
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
KCat/KM [mM/s]
EC Number
kcat/KM Value [1/mMs-1]
kcat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.018
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.062
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.13
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.18
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.35
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.42
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.45
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.95
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.3
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.3
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.4
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.5
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.6
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.8
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.2
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.5
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.7
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3.3
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3.7
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
4.3
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
5.7
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
6.3
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
7.3
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
8.3
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
8.7
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
10.1
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.2
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.3
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.8
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.3
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.3
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.7
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
15
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
15.1
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
16
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
18.3
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
20
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
21.7
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
25
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
25
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
26.7
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
26.7
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
28.3
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
30
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
30
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
31.7
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
31.7
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
35
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
36.7
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
36.7
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
40
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
43.3
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
45
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
63.3
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
83.3
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
93.3
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
183.3
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
183.3
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
233.3
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus
KCat/KM [mM/s] (protein specific)
EC Number
KCat/KM Value [1/mMs-1]
KCat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
1.1.1.149
0.018
-
geraniol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.062
-
4-oxo-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.13
-
3-deoxyglucosone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.18
-
ketotifen
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.35
-
isocaproaldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.42
-
trans-benzene dihydrodiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.45
-
4-chromanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
0.95
-
all-trans-retinal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1
-
alpha-tetralone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.3
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.3
-
acetoin
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.4
-
methylglyoxal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.5
-
(S)-1-indanol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.6
-
4-hydroxy-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
1.8
-
4-oxo-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2
-
menadione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2
-
(S)-1-tetralol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.2
-
pyridine 3-aldehyde
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.5
-
acrolein
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
2.7
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3
-
5alpha-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3.3
-
trans-2-hexenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
3.7
-
trans-2-nonenal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
4.3
-
testosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
5.7
-
hexanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
6.3
-
5beta-Pregnan-3alpha,21-diol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
7.3
-
5alpha-dihydrotestosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
8.3
-
diacetyl
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
8.7
-
17beta-estradiol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
10.1
-
beta-ionol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.2
-
befunolol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.3
-
5beta-Androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
13.8
-
5alpha-Androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.3
-
5alpha-androstan-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.3
-
5alpha-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
14.7
-
Estrone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
15
-
7alpha-hydroxy-dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
15.1
-
estrone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
16
-
5beta-androstan-3beta-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
18.3
-
dehydroepiandrosterone 3-sulfate
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
20
-
5alpha-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
21.7
-
20alpha-hydroxyprogesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
25
-
5alpha-pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
25
-
5beta-androstan-17beta-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
26.7
-
5beta-pregnan-20alpha-ol-3-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
26.7
-
dehydroepiandrosterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
28.3
-
5beta-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
30
-
5alpha-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
30
-
5beta-Pregnan-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
31.7
-
4-pregnen-3alpha-ol-20-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
31.7
-
5-androstene-3beta,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
35
-
Nonanal
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
36.7
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
36.7
-
5beta-pregnan-3alpha,20alpha-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
40
-
5beta-Androstan-3alpha-ol-17-one
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
43.3
-
4-androstene-3,17-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
45
-
progesterone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
63.3
-
5alpha-androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
83.3
-
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
93.3
-
4-Nitroacetophenone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
183.3
-
2-tert-butyl-1,4-benzoquinone
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
183.3
-
5beta-Androstan-3alpha,17beta-diol
at pH 7.4 and 37°C
Oryctolagus cuniculus
1.1.1.149
233.3
-
isatin
at pH 7.4 and 37°C
Oryctolagus cuniculus