BRENDA - Enzyme Database

Mobile phones electromagnetic radiation and NAD

Hagras, A.; Toraih, E.; Fawzy, M.; Biochimie Open 3, 19-25 (2016)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
1.1.1.41
diagnostics
enzyme NAD+-dependent isocitrate dehydrogenase cann act as a mitochondrial marker in asthenozoospermia
Homo sapiens
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.1.1.41
mitochondrion
-
Homo sapiens
5739
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Homo sapiens
-
2-oxoglutarate + CO2 + NADH
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.41
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.41
spermatozoon
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
740114
Homo sapiens
2-oxoglutarate + CO2 + NADH
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
1.1.1.41
heterotetramer
(alpha)2betagamma
Homo sapiens
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.1.1.41
37
-
assay at
Homo sapiens
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Homo sapiens
Application (protein specific)
EC Number
Application
Commentary
Organism
1.1.1.41
diagnostics
enzyme NAD+-dependent isocitrate dehydrogenase cann act as a mitochondrial marker in asthenozoospermia
Homo sapiens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Homo sapiens
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.1.1.41
mitochondrion
-
Homo sapiens
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Homo sapiens
-
2-oxoglutarate + CO2 + NADH
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.41
spermatozoon
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
740114
Homo sapiens
2-oxoglutarate + CO2 + NADH
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
1.1.1.41
heterotetramer
(alpha)2betagamma
Homo sapiens
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
1.1.1.41
37
-
assay at
Homo sapiens
General Information
EC Number
General Information
Commentary
Organism
1.1.1.41
malfunction
IDH activity is increased in patients with prolonged cell phone daily use over 4 h/day. Its level correlates negatively with either the motility ratio percentages or the progressive motility percentages in the study groups. NAD+-IDH in human seminal plasma can be one of seminal plasma biomarkers reflecting the mitochondrial function of spermatozoa. Alteration of its level reflect the defective motility of sperms among some cases of cellular phone users
Homo sapiens
1.1.1.41
metabolism
NAD-IDH is a key enzyme in the tricarboxylic acid cycle
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
1.1.1.41
malfunction
IDH activity is increased in patients with prolonged cell phone daily use over 4 h/day. Its level correlates negatively with either the motility ratio percentages or the progressive motility percentages in the study groups. NAD+-IDH in human seminal plasma can be one of seminal plasma biomarkers reflecting the mitochondrial function of spermatozoa. Alteration of its level reflect the defective motility of sperms among some cases of cellular phone users
Homo sapiens
1.1.1.41
metabolism
NAD-IDH is a key enzyme in the tricarboxylic acid cycle
Homo sapiens