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Literature summary extracted from

  • Ye, Q.; Yang, Y.; van Staalduinen, L.; Crawley, S.W.; Liu, L.; Brennan, S.; Cote, G.P.; Jia, Z.
    Structure of the Dictyostelium myosin-II heavy chain kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation (2016), Sci. Rep., 6, 26634.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.7
-
 Dictyostelium discoideum

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.11.7 alpha-kinase domain of myosin-II heavy chain kinase A, hanging drop vapor diffusion method, using 5% PEG (w/v) 8000, 20% (w/v) PEG 300, 10% (v/v) glycerol and 0.1 M Tris-HCl, pH 9.0 Dictyostelium discoideum

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.7 D663A inactive Dictyostelium discoideum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.7 ATP + [myosin II heavy-chain] Dictyostelium discoideum
-
 ADP + [myosin II heavy-chain] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.7 Dictyostelium discoideum P42527
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.7
-
 Dictyostelium discoideum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.7 ATP + myelin basic protein
-
 Dictyostelium discoideum ?
-
 ?
2.7.11.7 ATP + [myosin II heavy-chain]
-
 Dictyostelium discoideum ADP + [myosin II heavy-chain] phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.7 A-CAT alpha-kinase domain of myosin-II heavy chain kinase A Dictyostelium discoideum
2.7.11.7 MHCK-A
-
 Dictyostelium discoideum
2.7.11.7 myosin-II heavy chain kinase A
-
 Dictyostelium discoideum