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Literature summary extracted from

  • Opoku-Temeng, C.; Sintim, H.O.
    Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols (2016), Sci. Rep., 6, 25445.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.85 Tannic acid inhibits both DisA and phosphodiesterase YybT Bacillus subtilis
2.7.7.85 theaflavin-3'-gallate specifically inhibits DisA but not phosphodiesterase YybT Bacillus subtilis
2.7.7.85 theaflavin-3,3'-digallate specifically inhibits DisA but not phosphodiesterase YybT Bacillus subtilis

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.85 Bacillus subtilis
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.7.7.85 disA
-
 Bacillus subtilis

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.7.7.85 0.0085
-
 pH 7.5, 30°C Bacillus subtilis theaflavin-3,3'-digallate
2.7.7.85 0.0236
-
 pH 7.5, 30°C Bacillus subtilis theaflavin-3'-gallate