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Literature summary extracted from

  • Sun, M.; Liao, S.; Zhang, L.; Wu, C.; Qi, N.; Lv, M.; Li, J.; Lin, X.; Zhang, J.; Xie, M.; Zhu, G.; Cai, J.
    Molecular and biochemical characterization of Eimeria tenella hexokinase (2016), Parasitol. Res., 115, 3425-3433.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.1 D217H about 7% of wild-type activity Eimeria tenella
2.7.1.1 N216K about 2% of wild-type activity Eimeria tenella
2.7.1.1 S159P complete loss of activity Eimeria tenella

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.1 mangiferin
-
 Eimeria tenella
2.7.1.1 quercetin
-
 Eimeria tenella

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.1 0.67
-
 D-glucose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 5.66
-
 2-deoxy-D-glucose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 13.76
-
 D-fructose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 16.9
-
 D-glucose mutant D217H, pH 9.0, 36°C Eimeria tenella
2.7.1.1 25.41
-
 D-mannose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 26.4
-
 D-glucose mutant N216K, pH 9.0, 36°C Eimeria tenella

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.1 50000
-
-
 Eimeria tenella
2.7.1.1 50500
-
-
 Eimeria tenella

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.1 Eimeria tenella A0A172WCE4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.1 oocyte
-
 Eimeria tenella
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.1 ATP + 2-deoxy-D-glucose
-
 Eimeria tenella ADP + 2-deoxy-D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-fructose
-
 Eimeria tenella ADP + D-fructose 6-phosphate
-
 ?
2.7.1.1 ATP + D-glucose
-
 Eimeria tenella ADP + D-glucose 6-phosphate
-
 ?
2.7.1.1 ATP + D-mannose poor substrate Eimeria tenella ADP + D-mannose 6-phosphate
-
 ?
2.7.1.1 additional information no substrate: D-galactose Eimeria tenella ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.1 ? x * 50500, calculated, x * 50000, SDS-PAGE Eimeria tenella

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.1 36
-
-
 Eimeria tenella

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.1.1 0.025
-
 D-mannose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 1.5
-
 D-fructose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 10.8
-
 D-glucose mutant N216K, pH 9.0, 36°C Eimeria tenella
2.7.1.1 33.7
-
 2-deoxy-D-glucose wild-type, pH 9.0, 36°C Eimeria tenella
2.7.1.1 39.7
-
 D-glucose mutant D217H, pH 9.0, 36°C Eimeria tenella
2.7.1.1 219
-
 D-glucose wild-type, pH 9.0, 36°C Eimeria tenella

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.1 9
-
-
 Eimeria tenella

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.1.1 Eimeria tenella calculated
-
 5.7

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.7.1.1 0.007
-
 pH 9.0, 36°C Eimeria tenella quercetin
2.7.1.1 0.086
-
 pH 9.0, 36°C Eimeria tenella mangiferin