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Literature summary extracted from

  • Stuchlova Horynova, M.; Vrablikova, A.; Stewart, T.J.; Takahashi, K.; Czernekova, L.; Yamada, K.; Suzuki, H.; Julian, B.A.; Renfrow, M.B.; Novak, J.; Raska, M.
    N-acetylgalactosaminide alpha2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathy (2015), Nephrol. Dial. Transplant., 30, 234-238.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.3.3 expressed in HEK-293 cells Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.3.3 54000
-
x * 54000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.3 additional information Homo sapiens the enzyme can sialylate GalNAc of galactose-deficient immunoglobulin A1 ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.3 Homo sapiens A0A024R8M1
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.3.3 Ni-NTA agarose column chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.3 CMP-N-acetylneuraminate + VPSTPPTPSPSTPPTPSPSCCHPR-GalNAc
-
Homo sapiens CMP + ?
-
?
2.4.3.3 additional information the enzyme can sialylate GalNAc of galactose-deficient immunoglobulin A1 Homo sapiens ?
-
?

Subunits

EC Number Subunits Comment Organism
2.4.3.3 ? x * 54000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.4.3.3 alpha2,6-sialyltransferase II
-
Homo sapiens
2.4.3.3 ST6GalNAc-II
-
Homo sapiens