Literature summary extracted from

Hung, R.J.; Yazdani, U.; Yoon, J.; Wu, H.; Yang, T.; Gupta, N.; Huang, Z.; van Berkel, W.J.; Terman, J.R.
Mical links semaphorins to F-actin disassembly (2010), Nature, 463, 823-827.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.13.225	Drosophila melanogaster	Q86BA1	-	-

General Information

EC Number	General Information	Comment	Organism
1.14.13.225	physiological function	Mical is both necessary and sufficient for semaphorin-plexin mediated F-actin reorganization in vivo. Mical directly binds F-actin and disassembles both individual and bundled actin filaments. Mical utilizes its redox activity to alter F-actin dynamics in vivo and in vitro	Drosophila melanogaster

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Release 2023.1 (January 2023)