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Literature summary extracted from

  • Lu, J.; Gu, J.
    Significance of beta-galactoside alpha2,6 sialyltranferase 1 in cancers (2015), Molecules, 20, 7509-7527.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine Homo sapiens
-
 CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine
-
 Homo sapiens CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.1 beta-galactoside alpha2,6 sialyltransferase 1
-
 Homo sapiens
2.4.3.1 ST6Gal I
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.4.3.1 Homo sapiens the enzyme expression is increased in cancer of colon, breast, cervix, choriocarcinomas, acute myeloid leukemias, liver, and brain up