Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Guevara-Hernandez, E.; Arvizu-Flores, A.A.; Lugo-Sanchez, M.E.; Velazquez-Contreras, E.F.; Castillo-Yanez, F.J.; Brieba, L.G.; Sotelo-Mundo, R.R.
    A novel viral thymidylate kinase with dual kinase activity (2015), J. Bioenerg. Biomembr., 47, 431-440.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.6 0.224
-
 ATP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.6 0.251
-
 dTDP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 0.092
-
 ATP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 0.11
-
 dTMP pH 7.5, temperature not specified in the publication white spot syndrome virus

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.6 white spot syndrome virus
-
-
-
2.7.4.9 white spot syndrome virus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + dTDP
-
 white spot syndrome virus ADP + dTTP
-
 ?
2.7.4.6 additional information sequential ordered bi-bi reaction mechanism. The enzyme additionally shows dTMP kinase activity, reaction of EC 2.7.4.9, using dTMP as a substrate to produce dTDP white spot syndrome virus ?
-
 ?
2.7.4.9 ATP + dTMP
-
 white spot syndrome virus ADP + dTDP
-
 ?
2.7.4.9 additional information sequential ordered bi-bi reaction mechanism. The enzyme additionally shows nucleoside-diphosphate kinase activity, reaction of EC 2.7.4.6, using dTDP as a substrate to produce dTTP white spot syndrome virus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.4.6 ORF454
-
 white spot syndrome virus
2.7.4.9 ORF454
-
 white spot syndrome virus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.4.6 0.89
-
 dTDP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 3.16
-
 ATP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 3.56
-
 dTMP pH 7.5, temperature not specified in the publication white spot syndrome virus

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.7.4.6 4
-
 dTDP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.6 34
-
 ATP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 32
-
 dTMP pH 7.5, temperature not specified in the publication white spot syndrome virus
2.7.4.9 34
-
 ATP pH 7.5, temperature not specified in the publication white spot syndrome virus