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Literature summary extracted from

  • Singh, P.; Rao, P.; Bhattacharya, R.
    Dose and time-dependent effects of cyanide on thiosulfate sulfurtransferase, 3-mercaptopyruvate sulfurtransferase, and cystathionine lambda-lyase activities (2013), J. Biochem. Mol. Toxicol., 27, 499-507.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.1.1 mitochondrion
-
 Mus musculus 5739
-
2.8.1.2 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.1.1 thiosulfate + cyanide Mus musculus
-
 sulfite + thiocyanate
-
 ?
2.8.1.2 3-mercaptopyruvate + cyanide Mus musculus
-
 pyruvate + thiocyanate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.1.1 Mus musculus
-
-
-
2.8.1.2 Mus musculus Q99J99
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.1.1 brain
-
 Mus musculus
-
2.8.1.1 kidney
-
 Mus musculus
-
2.8.1.1 liver
-
 Mus musculus
-
2.8.1.2 brain
-
 Mus musculus
-
2.8.1.2 kidney
-
 Mus musculus
-
2.8.1.2 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.1.1 thiosulfate + cyanide
-
 Mus musculus sulfite + thiocyanate
-
 ?
2.8.1.2 3-mercaptopyruvate + cyanide
-
 Mus musculus pyruvate + thiocyanate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.1.1 TST
-
 Mus musculus
2.8.1.2 3-MPST
-
 Mus musculus

Expression

EC Number Organism Comment Expression
2.8.1.1 Mus musculus the hepatic and renal enzyme activity increases by 0.5 LD50 potassium cyanide up
2.8.1.2 Mus musculus the hepatic and renal enzyme activity increases by 0.5 LD50 potassium cyanide. Elevated renal cyanide level is also accompanied by increased enzyme activity up