EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.98.4 | Kitasatospora aureofaciens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.98.4 | 7-chloro-5a,11a-dehydrotetracycline + reduced cosynthetic factor-1 | - |
Kitasatospora aureofaciens | 7-chlorotetracycline + oxidized cosynthetic factor-1 | - |
? | |
1.3.98.4 | tetracycline + oxidized coenzyme F420 | - |
Kitasatospora aureofaciens | 5a,11a-dehydrotetracycline + reduced coenzyme F420 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.98.4 | additional information | cosynthetic factor-1 enables Streptomyces aureofaciens to produce tetracycline instead of their 5a,11a-dehydro analogues | Kitasatospora aureofaciens | |
1.3.98.4 | additional information | isolation of Cosynthetic Factor I, required for catayltic activity. The factor is dialysable and stable to autoclaving over the pH range of 1 to 10 | Kitasatospora aureofaciens |