EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.7.23 | gene LdUAP1, DNA and amino acid sequence determination and analysis, quantitative real-time quantitative PCR expression analysis | Leptinotarsa decemlineata |
2.7.7.23 | gene LdUAP2, DNA and amino acid sequence determination and analysis, quantitative real-time quantitative PCR expression analysis | Leptinotarsa decemlineata |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.7.23 | additional information | knockdown of LdUAP1 or combined knockdown of LdUAP1 and LdUAP2 | Leptinotarsa decemlineata |
2.7.7.23 | additional information | knockdown of LdUAP2 or combined knockdown of LdUAP1 and LdUAP2 | Leptinotarsa decemlineata |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate | Leptinotarsa decemlineata | - |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.23 | Leptinotarsa decemlineata | KT282116 | - |
- |
2.7.7.23 | Leptinotarsa decemlineata | KT282117 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.7.23 | epidermis | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | fat body | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | foregut | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | ganglion | ventral | Leptinotarsa decemlineata | - |
2.7.7.23 | hemocyte | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | hindgut | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | larva | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | malpighian tubule | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | midgut | - |
Leptinotarsa decemlineata | - |
2.7.7.23 | additional information | developmental expression pattern of enzyme LdUAP1, tissue and temporal expression profiles of LdUAP1 and LdUAP2, overview | Leptinotarsa decemlineata | - |
2.7.7.23 | additional information | developmental expression pattern of enzyme LdUAP2, tissue and temporal expression profiles of LdUAP1 and LdUAP2, overview | Leptinotarsa decemlineata | - |
2.7.7.23 | muscle | thoracic | Leptinotarsa decemlineata | - |
2.7.7.23 | trachea | - |
Leptinotarsa decemlineata | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate | - |
Leptinotarsa decemlineata | diphosphate + UDP-N-acetyl-alpha-D-glucosamine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.23 | UAP1 | - |
Leptinotarsa decemlineata |
2.7.7.23 | UAP2 | - |
Leptinotarsa decemlineata |
2.7.7.23 | uridine diphosphate N-acetylglucosamine pyrophosphorylase | - |
Leptinotarsa decemlineata |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.7.7.23 | Leptinotarsa decemlineata | a decrease in 20-hydroxyecdysone by RNAi of an ecdysteroidogenesis gene SHD and a 20E signaling gene FTZ-F1 repress the expression | down |
2.7.7.23 | Leptinotarsa decemlineata | a decrease in 20-hydroxyecdysone by RNAi of an ecdysteroidogenesis gene SHD and a 20E signaling gene FTZ-F1 repress the expression. Juvenile hormone, juvenile hormone analog pyriproxyfen and an increase in juvenile hormone by RNAi of allatostatin gene AS-C downregulate UAP1 | down |
2.7.7.23 | Leptinotarsa decemlineata | a decrease in 20-hydroxyecdysone by RNA interference of an ecdysteroidogenesis gene LdSHD and a 20-hydroxyecdysone signaling gene LdFTZ-F1 repress the expression of the two LdUAPs in Leptinotarsa decemlineata. A decrease in Juvenile hormone (JH) by silencing of a JH biosynthesis gene LdJHAMT downregulates LdUAP1 converse effects | down |
2.7.7.23 | Leptinotarsa decemlineata | a decrease in 20-hydroxyecdysone by RNA interference of an ecdysteroidogenesis gene LdSHD and a 20-hydroxyecdysone signaling gene LdFTZ-F1 repress the expression of the two LdUAPs in Leptinotarsa decemlineata. Juvenile hormone (JH), a JH analogue pyriproxyfen and an increase in JH by RNAi of an allatostatin gene LdAS-C downregulate LdUAP1 | down |
2.7.7.23 | Leptinotarsa decemlineata | 20-hydroxyecdysone and ecdysteroid agonist halofenozide activate the expression of the UAP1 | up |
2.7.7.23 | Leptinotarsa decemlineata | 20-hydroxyecdysone and ecdysteroid agonist halofenozide activate the expression of the UAP2. Juvenile hormone, juvenile hormone analog pyriproxyfen and an increase in juvenile hormone by RNAi of allatostatin gene AS-C upregulate UAP2 | up |
2.7.7.23 | Leptinotarsa decemlineata | 20-hydroxyecdysone and an ecdysteroid agonist halofenozide activated the expression of the two LdUAPs in Leptinotarsa decemlineata. A decrease in Juvenile hormone (JH) by silencing of a JH biosynthesis gene LdJHAMT upregulates LdUAP1 converse effects | up |
2.7.7.23 | Leptinotarsa decemlineata | 20-hydroxyecdysone and an ecdysteroid agonist halofenozide activated the expression of the two LdUAPs in Leptinotarsa decemlineata. Juvenile hormone (JH), a JH analogue pyriproxyfen and an increase in JH by RNAi of an allatostatin gene LdAS-C upregulate LdUAP2 | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.7.23 | malfunction | knockdown of LdUAP1 reduces chitin contents in whole larvae and integument samples, thins tracheal taenidia, impairs larval-larval molt, larval-pupal ecdysis and adult emergence. Combined knockdown of LdUAP1 and LdUAP2 causes an additive negative effect. Phenotypes, overview | Leptinotarsa decemlineata |
2.7.7.23 | malfunction | silencing of LdUAP2 significantly reduces foliage consumption, decreases chitin content in midgut samples, damages PM, and retards larval growth. The resulting larvae have lighter fresh weights, smaller body sizes and depleted fat body. As a result, the development is arrested. Combined knockdown of LdUAP1 and LdUAP2 causes an additive negative effect. Phenotypes, overview | Leptinotarsa decemlineata |
2.7.7.23 | physiological function | knockdown of UAP1 reduces chitin contents in whole larvae and integument samples, thinned tracheal taenidia, impairs larval-larval molt, larval-pupal ecdysis and adult emergence. Combined knockdown of UAP1 and UAP2 causes an additive negative effect | Leptinotarsa decemlineata |
2.7.7.23 | physiological function | silencing of LdUAP2 significantly reduces foliage consumption, decreases chitin content in midgut samples, damages peritrophic matrix, and retards larval growth | Leptinotarsa decemlineata |
2.7.7.23 | physiological function | the enzyme is involved in the biosynthesis of chitin, an essential component of the epidermal cuticle and midgut peritrophic matrix in insects | Leptinotarsa decemlineata |