EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.3.1 | the truncated DELTA89 and DELTA108 variants of the recombinant human enzyme are expressed in human embryonic kidney cells | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.3.1 | additional information | the DELTA108 mutant enzyme shows only sialyl transferase activity with specificity for mono-sialylation and a Km value for 6'-sialyl-N-acetyl-D-lactosamine of 84 mM while the DELTA89 mutant show a Km value for 6'-sialyl-N-acetyl-D-lactosamine of 8.3 mM | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.3.1 | Golgi apparatus | - |
Homo sapiens | 5794 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.1 | CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | Homo sapiens | - |
CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.3.1 | Homo sapiens | P15907 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.1 | CMP-N-acetylneuraminate + 6'-sialyl-N-acetyl-D-lactosamine | - |
Homo sapiens | ? | - |
? | |
2.4.3.1 | CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | - |
Homo sapiens | CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.3.1 | beta-galactoside alpha2,6 sialyltransferase I | - |
Homo sapiens |
2.4.3.1 | ST6Gal-I | - |
Homo sapiens |