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Literature summary extracted from

  • Sousa, C.S.; Barros, B.A.; Barh, D.; Ghosh, P.; Azevedo, V.; Barros, E.G.; Moreira, M.A.
    In silico characterization of 1,2-diacylglycerol cholinephosphotransferase and lysophosphatidylcholine acyltransferase genes in Glycine max L. Merrill (2016), Genet. Mol. Res., 15, gmr.15038974.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.2 gene GLYMA_12G0819001, DNA and amino acid sequence determination, analysis, and comparison, gene modeling using sequences Glyma02g14210 and Glyma12g08720, the soybean genome possesses two loci encoding the enzyme CPT, overview. Presence of binding sites for DNA-binding with one finger proteins in promoter regions of the gene model encoding CPT Glycine max

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.2 endoplasmic reticulum membrane a transmembrane enzyme Glycine max 5789
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.2 CDP-choline + 1,2-diacyl-sn-glycerol Glycine max
-
 CMP + a phosphatidylcholine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.2 Glycine max Q39810 gene GLYMA_12G0819001 or glyma12g08720
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.2 flower
-
 Glycine max
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2.7.8.2 leaf young Glycine max
-
2.7.8.2 additional information tissue-specific enzyme expression analysis by virtual expression analysis from RNASeq data Glycine max
-
2.7.8.2 pod
-
 Glycine max
-
2.7.8.2 root
-
 Glycine max
-
2.7.8.2 root nodule
-
 Glycine max
-
2.7.8.2 seed
-
 Glycine max
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.2 CDP-choline + 1,2-diacyl-sn-glycerol
-
 Glycine max CMP + a phosphatidylcholine
-
 r

Subunits

EC Number Subunits Comment Organism
2.7.8.2 More the enzyme contains domains for a CDP-alcohol phosphatidyltransferase, choline/ethanolamine phosphotransferase, and signal peptide and transmembrane regions (nine transmembrane regions in the protein encoded by Glyma12g08720 and eight transmembrane regions in the protein encoded by Glyma02g14210) Glycine max

Synonyms

EC Number Synonyms Comment Organism
2.7.8.2 1,2-diacylglycerol cholinephosphotransferase
-
 Glycine max
2.7.8.2 CPT
-
 Glycine max
2.7.8.2 Glyma02g14210 locus name Glycine max
2.7.8.2 Glyma12g08720 locus name Glycine max
2.7.8.2 GLYMA_12G0819001
-
 Glycine max

Expression

EC Number Organism Comment Expression
2.7.8.2 Glycine max gene cis-elements respond to biotic and abiotic stress, the enzyme is expressed under conditions of water or salinity stress, during infection with pathogens, in response to salicylic acid signaling, during somatic embryo differentiation, in immature seeds, in root tissues, and in soybean calli grown in the dark up

General Information

EC Number General Information Comment Organism
2.7.8.2 metabolism CPT is a key enzyme in the metabolism of oil in soybean seeds, the enzyme is involved in lipid biosynthesis in soybean seeds and is important for triacylglycerol biosynthesis, together with lysophosphatidylcholine acyltransferase, EC 2.3.1.23. diacylglycerol can also be converted to triacylglycerol by acylation at position 3 of the glycerol molecule in a reaction catalyzed by diacylglycerol acyltransferase, EC 2.3.1.20 Glycine max
2.7.8.2 physiological function the enzyme produces membrane lipids by reversibly converting diacylglycerol into phosphatidylcholine, which is a substrate for polyunsaturated fatty acid biosynthesis and can replenish the pool of acyl-CoA through the action of cytoplasmic lysophosphatidylcholine acyltransferase Glycine max