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Literature summary extracted from

  • Tanoue, R.; Kobayashi, M.; Katayama, K.; Nagata, N.; Wada, H.
    Phosphatidylglycerol biosynthesis is required for the development of embryos and normal membrane structures of chloroplasts and mitochondria in Arabidopsis (2014), FEBS Lett., 588, 1680-1685.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.5 phosphatidylglycerophosphate synthase is encoded by PGP1 and PGP2 in Arabidopsis thaliana Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
2.7.8.5 additional information isolation of naturally occuring pgp1/pgp2 double mutant pgp1–2, phenotype,overview Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.5 chloroplast PGP1 Arabidopsis thaliana 9507
-
2.7.8.5 endoplasmic reticulum PGP2, probably Arabidopsis thaliana 5783
-
2.7.8.5 microsome PGP2 Arabidopsis thaliana
-
-
2.7.8.5 mitochondrion PGP1 Arabidopsis thaliana 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.5 CDP-diacylglycerol + sn-glycerol 3-phosphate Arabidopsis thaliana
-
 CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.5 Arabidopsis thaliana O80952 PGPS1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.5 embryo
-
 Arabidopsis thaliana
-
2.7.8.5 leaf
-
 Arabidopsis thaliana
-
2.7.8.5 seed
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.5 CDP-diacylglycerol + sn-glycerol 3-phosphate
-
 Arabidopsis thaliana CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.5 PGP synthase
-
 Arabidopsis thaliana
2.7.8.5 PGPS1
-
 Arabidopsis thaliana
2.7.8.5 PGPS2
-
 Arabidopsis thaliana
2.7.8.5 phosphatidylglycerophosphate synthase
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.7.8.5 malfunction an isolated pgp1/pgp2 double mutant pgp1-2 of Arabidopsis thaliana shows delayed embryo development, the majority of seeds from the mutant do not germinate, mutant thylakoid membranes do not develop in plastids, mitochondrial membrane structures are abnormal in the mutant embryos, and radiolabeling of phospholipids shows that radioactivity is not significantly incorporated into phosphatidylglycerol. Structures of chloroplasts and mitochondria in embryonic cells of pgp1-2 and pgp1-2pgp2, and phenotypes, detailed overview Arabidopsis thaliana
2.7.8.5 metabolism phosphatidylglycerophosphate synthase catalyzes a committed step in the biosynthesis of phosphatidylglycerol Arabidopsis thaliana
2.7.8.5 physiological function phosphatidylglycerol biosynthesis by the enzyme is essential for the development of embryos and normal membrane structures of chloroplasts and mitochondria in Arabidopsis thaliana Arabidopsis thaliana