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Literature summary extracted from

  • Villanueva, L.; Schouten, S.; Sinninghe Damste, J.S.
    Depth-related distribution of a key gene of the tetraether lipid biosynthetic pathway in marine Thaumarchaeota (2015), Environ. Microbiol., 17, 3527-3539.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.41 diversity of thaumarchaeotal GGGP synthases in the marine water column, phylogenetic analysis and tree and correlation to the classification of shallow and deep water clusters, overview Thaumarchaeota

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.41 geranylgeranyl diphosphate + sn-glycerol 1-phosphate Thaumarchaeota
-
 diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.41 Thaumarchaeota
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.41 geranylgeranyl diphosphate + sn-glycerol 1-phosphate
-
 Thaumarchaeota diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.41 geranylgeranylglyceryl phosphate synthase
-
 Thaumarchaeota
2.5.1.41 GGGP synthase
-
 Thaumarchaeota

General Information

EC Number General Information Comment Organism
2.5.1.41 evolution diversity of thaumarchaeotal GGGP synthases in the marine water column, phylogenetic analysis and tree and correlation to the classification of shallow and deep water clusters, overview. Differences in isoprenoid glycerol dialkyl glycerol tetraethers distributions from subsurface to deep waters that may be explained by differences in the GGGP synthase, suggesting a genetic control on isoprenoid glycerol dialkyl glycerol tetraethers distribution. Diversity of archaeal GGGP synthases, overview Thaumarchaeota
2.5.1.41 metabolism key enzyme of the thaumarchaeotal lipid biosynthetic pathway Thaumarchaeota
2.5.1.41 physiological function the key enzyme catalyses the formation of an ether bond between isoprenyl diphosphate and glycerol-1-phosphate to form 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate, and is the first committed step towards ether membrane lipid synthesis Thaumarchaeota