EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.20 | adenosine | substrate inhibition, presence of ATP relieves substrate inhibition by adenosine | Toxoplasma gondii | |
2.7.1.20 | ADP | noncompetitive with adenosine, ADP and ATP show additive effects | Toxoplasma gondii | |
2.7.1.20 | AMP | competitive with ATP, noncompetitive with adenosine | Toxoplasma gondii | |
2.7.1.20 | ATP | noncompetitive with adenosine, ADP and ATP show additive effects | Toxoplasma gondii |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.20 | 0.002 | - |
adenosine | pH 7.4, 37°C | Toxoplasma gondii | |
2.7.1.20 | 0.05 | - |
ATP | pH 7.4, 37°C | Toxoplasma gondii |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.20 | Toxoplasma gondii | Q9TVW2 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.20 | ADP + adenosine | 47.7% conversion | Toxoplasma gondii | 2 AMP | - |
? | |
2.7.1.20 | ATP + adenosine | 96.2% conversion | Toxoplasma gondii | ADP + AMP | - |
? | |
2.7.1.20 | dADP + adenosine | 28.5% conversion | Toxoplasma gondii | dAMP + AMP | - |
? | |
2.7.1.20 | GDP + adenosine | 21.1% conversion | Toxoplasma gondii | GMP + AMP | - |
? | |
2.7.1.20 | additional information | hybrid random bi-uni ping-pong uni-bi mechanism, with substrate-enzyme-cosubstrate complex formation, binding pattern indicates that binding of the substrate interferes with the binding of the cosubstrate and vice versa. For every ATP consumed, the enzyme generates three AMPs | Toxoplasma gondii | ? | - |
? | |
2.7.1.20 | UDP + adenosine | 5.9% conversion | Toxoplasma gondii | UMP + AMP | - |
? |