Literature summary extracted from

Malnuit, V.; Slavetinska, L.P.; Naus, P.; Dzubak, P.; Hajduch, M.; Stolarikova, J.; Snasel, J.; Pichova, I.; Hocek, M.
2-substituted 6-(het)aryl-7-deazapurine ribonucleosides: synthesis, inhibition of adenosine kinases, and antimycobacterial activity (2015), ChemMedChem, 10, 1079-1093.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.20	2-fluoro-4-(benzofuran-2-yl)-7-(beta-d-ribofuranosyl)-7H-pyrrolo-[2,3-d]pyrimidine	potent and selective inhibition, moderate effect against whole cells. MIC value 62.5 microM	Mycobacterium tuberculosis

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.20	Mycobacterium tuberculosis	-	-	-
2.7.1.20	Mycobacterium tuberculosis My 331/88	-	-	-

IC50 Value

EC Number	IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
2.7.1.20	0.0000012	-	pH not specified in the publication, temperature not specified in the publication	Mycobacterium tuberculosis	2-fluoro-4-(benzofuran-2-yl)-7-(beta-d-ribofuranosyl)-7H-pyrrolo-[2,3-d]pyrimidine

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Release 2023.1 (January 2023)