Literature summary extracted from

Zhang, G.; Huang, H.; Liu, D.; Cheng, Y.; Liu, X.; Zhang, W.; Yin, R.; Zhang, D.; Zhang, P.; Liu, J.; Li, C.; Liu, B.; Luo, Y.; Zhu, Y.; Zhang, N.; He, S.; He, C.; Wang, H.; Chen, D.
N6-methyladenine DNA modification in Drosophila (2015), Cell, 161, 893-906.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.14.11.51	300000	-	gel filtration	Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.11.51	N6-methyladenine in DNA + 2-oxoglutarate + O2	Drosophila melanogaster	-	adenine in DNA + formaldehyde + succinate + CO2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.11.51	Drosophila melanogaster	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.11.51	embryo	-	Drosophila melanogaster	-
1.14.11.51	ovary	-	Drosophila melanogaster	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.11.51	N6-methyladenine in DNA + 2-oxoglutarate + O2	-	Drosophila melanogaster	adenine in DNA + formaldehyde + succinate + CO2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.11.51	DMAD	-	Drosophila melanogaster
1.14.11.51	DNA 6mA demethylase	-	Drosophila melanogaster

General Information

EC Number	General Information	Comment	Organism
1.14.11.51	physiological function	the enzyme promotes differentiation of early germ cells in fly ovary	Drosophila melanogaster

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)