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Literature summary extracted from

  • Qian, Z.; Zhao, J.; Bai, X.; Tong, W.; Chen, Z.; Wei, H.; Wang, Q.; Liu, S.
    Thermal stability of glucokinases in Thermoanaerobacter tengcongensis (2013), BioMed Res. Int., 2013, 646539.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.2 2.4
-
 D-glucose pH 8.0, 75°C Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 0.9
-
 ADP pH 8.0, 75°C Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 2.1
-
 D-glucose pH 8.0, 75°C Caldanaerobacter subterraneus subsp. tengcongensis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.2 Ca2+ 13.4% of the activity with Mg2+ Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.2 Cu2+ 0.4% of the activity with Mg2+ Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.2 Mg2+ required, best activating cation Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 Mg2+ required Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 additional information Ca2+ or Cu2+ cannot substitute for Mg2+ Caldanaerobacter subterraneus subsp. tengcongensis

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.2 Caldanaerobacter subterraneus subsp. tengcongensis Q8RDE9
-
-
2.7.1.2 Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 Q8RDE9
-
-
2.7.1.147 Caldanaerobacter subterraneus subsp. tengcongensis Q8R8N4
-
-
2.7.1.147 Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 Q8R8N4
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.2 ADP + D-glucose 3% of the velocity with ATP Caldanaerobacter subterraneus subsp. tengcongensis AMP + D-glucose 6-phosphate
-
 ?
2.7.1.2 ATP + D-fructose 3% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis ADP + D-fructose 6-phosphate
-
 ?
2.7.1.2 ATP + D-fructose 3% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 ADP + D-fructose 6-phosphate
-
 ?
2.7.1.2 ATP + D-glucose
-
 Caldanaerobacter subterraneus subsp. tengcongensis ADP + D-glucose 6-phosphate
-
 ?
2.7.1.2 ATP + D-glucose
-
 Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 ADP + D-glucose 6-phosphate
-
 ?
2.7.1.2 ATP + D-mannose 99% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis ADP + D-mannose 6-phosphate
-
 ?
2.7.1.2 ATP + D-mannose 99% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 ADP + D-mannose 6-phosphate
-
 ?
2.7.1.2 CTP + D-glucose 38% of the velocity with ATP Caldanaerobacter subterraneus subsp. tengcongensis CDP + D-glucose 6-phosphate
-
 ?
2.7.1.2 CTP + D-glucose 38% of the velocity with ATP Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 CDP + D-glucose 6-phosphate
-
 ?
2.7.1.2 additional information no substrate: N-acetyl-D-glucosamine, D-galactose Caldanaerobacter subterraneus subsp. tengcongensis ?
-
 ?
2.7.1.2 additional information no substrate: N-acetyl-D-glucosamine, D-galactose Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 ?
-
 ?
2.7.1.147 ADP + D-glucose
-
 Caldanaerobacter subterraneus subsp. tengcongensis AMP + D-glucose 6-phosphate
-
 ?
2.7.1.147 ADP + D-glucose
-
 Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 AMP + D-glucose 6-phosphate
-
 ?
2.7.1.147 ADP + D-mannose 17% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis AMP + D-mannose 6-phosphate
-
 ?
2.7.1.147 ADP + D-mannose 17% of the velocity with D-glucose Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 AMP + D-mannose 6-phosphate
-
 ?
2.7.1.147 additional information enzyme effectively utilizes glucose and cannot efficiently catalyze mannose, and 2-deoxyglucose. No activity with ATP, CTP, GTP, phosphoenolpyruvate Caldanaerobacter subterraneus subsp. tengcongensis ?
-
 ?
2.7.1.147 additional information enzyme effectively utilizes glucose and cannot efficiently catalyze mannose, and 2-deoxyglucose. No activity with ATP, CTP, GTP, phosphoenolpyruvate Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.2 NagC
-
 Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.2 TTE0090
-
 Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 NagC4
-
 Caldanaerobacter subterraneus subsp. tengcongensis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.2 75
-
-
 Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 80
-
-
 Caldanaerobacter subterraneus subsp. tengcongensis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.2 8
-
-
 Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.147 8
-
-
 Caldanaerobacter subterraneus subsp. tengcongensis

General Information

EC Number General Information Comment Organism
2.7.1.2 metabolism the abundance enzme is attenuated when culture temperature is elevated and is almost undetectable at 80°C. The glucokinase interacts with heat shock protein HSP60 at 60°C and 75°C Caldanaerobacter subterraneus subsp. tengcongensis