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Literature summary extracted from

  • Wang, Z.; Yang, X.; Chen, L.; Zhi, X.; Lu, H.; Ning, Y.; Yeong, J.; Chen, S.; Yin, L.; Wang, X.; Li, X.
    Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury (2016), Arch. Toxicol., 91, 271-287.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.2 Mus musculus O35400
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.2 hepatic oval cell
-
 Mus musculus
-
2.8.2.2 WB-F344 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.2 3'-phosphoadenylylsulfate + 22-hydroxycholesterol
-
 Mus musculus adenosine 3',5'-bisphosphate + 22-hydroxycholesterol sulfate
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + 24,25-epoxycholesterol
-
 Mus musculus adenosine 3',5'-bisphosphate + 24,25-epoxycholesterol sulfate
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + 25-hydroxycholesterol
-
 Mus musculus adenosine 3',5'-bisphosphate + 25-hydroxycholesterol sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.2 hydroxysteroid sulfotransferase 2B1b
-
 Mus musculus
2.8.2.2 SULT2B1b
-
 Mus musculus

Expression

EC Number Organism Comment Expression
2.8.2.2 Mus musculus the expression of SULT2B1b is increased dramatically in a chemical-induced liver injury model, mainly in hepatic oval cells up

General Information

EC Number General Information Comment Organism
2.8.2.2 physiological function upregulation of SULT2B1b promotes hepatic oval cell proliferation and aggravate liver injury via the suppression of oxysterol-induced LXR activation in chemically induced mouse liver injury Mus musculus