EC Number | Cloned (Comment) | Organism |
---|---|---|
2.5.1.18 | expressed in Escherichia coli | Danio rerio |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.18 | 0.004 | - |
monochlorobimane | isoform Gstt1a, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.05 | - |
monochlorobimane | isoform GstrI, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.11 | - |
monochlorobimane | isoform Gstm3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.18 | - |
monochlorobimane | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.2 | - |
Ethacrynic acid | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.22 | - |
monochlorobimane | isoform Gstm1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.24 | - |
Ethacrynic acid | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.25 | - |
monochlorobimane | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.27 | - |
glutathione | isoform Gstz1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.27 | - |
Dichloroacetic acid | isoform Gstz1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.28 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.32 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstt1a, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.39 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.5 | - |
glutathione | isoform Gstr1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.58 | - |
glutathione | isoform Gstm1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.58 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstr1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.75 | - |
glutathione | isoform Gsta3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.82 | - |
glutathione | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 1.08 | - |
dehydroascorbate | isoform Gsto2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 1.19 | - |
glutathione | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 1.68 | - |
1-chloro-2,4-dinitrobenzene | isoform Gsta3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 2.05 | - |
glutathione | isoform Gstm3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 2.24 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstm1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 2.91 | - |
glutathione | isoform Gsto2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 3.69 | - |
1-chloro-2,4-dinitrobenzene | isoform Gstm3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 4.44 | - |
glutathione | isoform Gstta1, at pH 6.5 and 25°C | Danio rerio |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.18 | cytosol | - |
Danio rerio | 5829 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.18 | Danio rerio | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.5.1.18 | Ni-NTA column chromatography, and gel filtration | Danio rerio |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.5.1.18 | brain | high expression of isoforms Gstz1, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | gill | high expression of isoforms Gsto2, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | intestine | high expression of isoforms Gsta, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | kidney | high expression of isoforms Gstz1, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | liver | high expression of isoforms Gstt1a, Gstz1, Gstp, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | ovary | high expression of isoforms Gsto2, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
2.5.1.18 | testis | high expression of isoforms Gsta, Gstp, Gstm, Gstr1, Mgst3a, and Mgst3b | Danio rerio | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.18 | 1-chloro-2,4-dinitrobenzene + glutathione | - |
Danio rerio | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
2.5.1.18 | dehydroascorbate + glutathione | substrate for isoform Gsto2 | Danio rerio | ? | - |
? | |
2.5.1.18 | dichloroacetic acid + glutathione | substrate for isoform Gstz1 | Danio rerio | ? | - |
? | |
2.5.1.18 | ethacrynic acid + glutathione | substrate for isoforms Gstp1 and Gstp2 | Danio rerio | ? | - |
? | |
2.5.1.18 | monochlorobimane + glutathione | - |
Danio rerio | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.5.1.18 | glutathione-S-transferas | - |
Danio rerio |
2.5.1.18 | GST | - |
Danio rerio |
2.5.1.18 | Gsta | isoform | Danio rerio |
2.5.1.18 | Gstm | isoform | Danio rerio |
2.5.1.18 | GSTO2 | isoform | Danio rerio |
2.5.1.18 | GSTP | isoform | Danio rerio |
2.5.1.18 | Gstr1 | isoform | Danio rerio |
2.5.1.18 | Gstt1a | isoform | Danio rerio |
2.5.1.18 | Gstz1 | isoform | Danio rerio |
2.5.1.18 | Mgst3a | isoform | Danio rerio |
2.5.1.18 | Mgst3b | isoform | Danio rerio |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.18 | 0.002 | - |
Dichloroacetic acid | isoform Gstz1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 0.005 | - |
glutathione | isoform Gstz1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 1.23 | - |
Ethacrynic acid | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 2.24 | - |
Ethacrynic acid | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 8.69 | - |
glutathione | isoform Gsto2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 11.2 | - |
glutathione | isoform Gstta1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 11.9 | - |
dehydroascorbate | isoform Gsto2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 14.1 | - |
glutathione | isoform Gstp2, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 16.6 | - |
glutathione | isoform Gsta3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 20.8 | - |
glutathione | isoform Gstr1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 22.7 | - |
glutathione | isoform Gstm1, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 57.2 | - |
glutathione | isoform Gstm3, at pH 6.5 and 25°C | Danio rerio | |
2.5.1.18 | 129 | - |
glutathione | isoform Gstp1, at pH 6.5 and 25°C | Danio rerio |