EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.2.B13 | expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.3.2.B13 | N-terminal domain in complex with von Hippel-Lindau tumor suppressor protein, elonhin B, and elongin C, hanging drop vapor diffusion method, using 5 M sodium formate as precipitant | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.B13 | S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-L-lysine | Homo sapiens | - |
[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.2.B13 | Homo sapiens | P40337 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.2.B13 | Ni-NTA column chromatography, glutatione S-transferase column chromatography, maltose binding protein-Trap column chromatography, anion exchange chromatorgaphy, and gel filtration | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.B13 | S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-L-lysine | - |
Homo sapiens | [cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.2.B13 | CRL | - |
Homo sapiens |
2.3.2.B13 | Cul2 E3 ligase | - |
Homo sapiens |
2.3.2.B13 | cullin 2 E3 ubiquitin ligase | - |
Homo sapiens |
2.3.2.B13 | cullin-RING E3 ubiquitin ligase | - |
Homo sapiens |