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Literature summary extracted from

  • Zhang, L.; Gao, B.; Wang, X.; Zhang, Z.; Liu, X.; Wang, J.; Mo, T.; Liu, Y.; Shi, S.; Tu, P.
    Identification of a new curcumin synthase from ginger and construction of a curcuminoid-producing unnatural fusion protein diketide-CoA synthase - curcumin synthase (2016), RSC Adv., 6, 12519-12524.
No PubMed abstract available

Application

EC Number Application Comment Organism
2.3.1.217 synthesis construction of a fusion protein diketide-CoA synthase::curcumin synthase. Comparing to CURS, the fusion protein shows similar substrate specificities and catalytic potentials to catalyze the formation of various curcuminoids, with increased yields of curcuminoids Zingiber officinale

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.217
-
 Zingiber officinale

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.217 Zingiber officinale
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.217 (4-coumaroyl)acetyl-CoA + 3-(4-hydroxyphenyl)propionyl-CoA + H2O
-
 Zingiber officinale 2 CoA + tetrahydrobisdemethoxycurcumin + CO2
-
 ?
2.3.1.217 feruloyl-CoA + feruloylacetyl-CoA + H2O
-
 Zingiber officinale 2 CoA + curcumin + CO2
-
 ?