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Literature summary extracted from

  • Cynis, H.; Funkelstein, L.; Toneff, T.; Mosier, C.; Ziegler, M.; Koch, B.; Demuth, H.U.; Hook, V.
    Pyroglutamate-amyloid-beta and glutaminyl cyclase are colocalized with amyloid-beta in secretory vesicles and undergo activity-dependent, regulated secretion (2014), Neurodegener. Dis., 14, 85-97.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.5 secretory vesicle
-
 Homo sapiens 99503
-
2.3.2.5 secretory vesicle
-
 Bos taurus 99503
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.5 48000
-
 x * 48000, SDS-PAGE Homo sapiens
2.3.2.5 48000
-
 x * 48000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.5 Bos taurus
-
-
-
2.3.2.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.5 adrenal medulla
-
 Bos taurus
-
2.3.2.5 IMR-32 cell
-
 Homo sapiens
-
2.3.2.5 neuroblastoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.5 L-glutaminyl-amyloid beta peptide
-
 Homo sapiens 5-oxoprolyl-amyloid beta peptide + NH3
-
 ?
2.3.2.5 L-glutaminyl-amyloid beta peptide
-
 Bos taurus 5-oxoprolyl-amyloid beta peptide + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.2.5 ? x * 48000, SDS-PAGE Homo sapiens
2.3.2.5 ? x * 48000, SDS-PAGE Bos taurus

Synonyms

EC Number Synonyms Comment Organism
2.3.2.5 glutaminyl cyclase
-
 Homo sapiens
2.3.2.5 glutaminyl cyclase
-
 Bos taurus