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Literature summary extracted from

  • Park, H.; Kim, Y.; Kim, K.; Kim, Y.; Yang, Y.; Jin, J.; Kim, Y.; Kim, B.; Shim, H.; Kim, Y.
    Comparative n-linked glycan analysis of wild-type and alpha1,3-galactosyltransferase gene knock-out pig fibroblasts using mass spectrometry approaches (2015), Mol. Cells, 38, 65-74.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.87 additional information generation of enzyme knockout mutant animals Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.87 UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R Sus scrofa
-
 UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.87 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.87 fibroblast cultured from ear skin biopsies Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.87 UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R
-
 Sus scrofa UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.87 alpha1,3-galactosyltransferase
-
 Sus scrofa
2.4.1.87 GALT
-
 Sus scrofa

General Information

EC Number General Information Comment Organism
2.4.1.87 malfunction absence of galactose-alpha-1,3-galactose residue in the GalT-KO pig cells results in a higher level of overall fucosylated N-glycans in GalT-KO pig fibroblasts compared to wild-type pig fibroblasts, the relative quantity of the N-glycolylneuraminic acid antigen is also slightly higher in the GalT-KO pigs, mutant phenotype, overview Sus scrofa
2.4.1.87 additional information identification and quantification of 47 N-glycans from wild-type and enzyme kockout pig fibroblasts using MALDI-TOF mass spectrometry, overview Sus scrofa