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Literature summary extracted from

  • Plumbridge, J.
    A mutation which affects both the specificity of PtsG sugar transport and the regulation of ptsG expression by Mlc in Escherichia coli (2000), Microbiology, 146, 2655-2663.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1] Escherichia coli
-
 [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1] Escherichia coli JM2053
-
 [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.199 Escherichia coli
-
-
-
2.7.1.199 Escherichia coli JM2053
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1]
-
 Escherichia coli [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1]
-
 Escherichia coli JM2053 [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.199 EIICBGlc
-
 Escherichia coli
2.7.1.199 PtsG
-
 Escherichia coli

Expression

EC Number Organism Comment Expression
2.7.1.199 Escherichia coli transcription of ptsG is regulated by the repressor Mlc down
2.7.1.199 Escherichia coli the umgC mutation (which allows a strain mutated in the mannose phosphotransferase system to grow on glucosamine) enhances enzyme mRNA levels up