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Literature summary extracted from

  • Park, H.S.; Kayser, K.J.; Kwak, J.H.; Kilbane, J.J.
    Heterologous gene expression in Thermus thermophilus: beta-galactosidase, dibenzothiophene monooxygenase, PNB carboxy esterase, 2-aminobiphenyl-2,3-diol dioxygenase, and chloramphenicol acetyl transferase (2004), J. Ind. Microbiol. Biotechnol., 31, 189-197.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.21 gene dszC, functional recombinant enzyme expression in Thermus thermophilus strain HB27 Rhodococcus erythropolis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.21 dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2 Rhodococcus erythropolis
-
 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
 ?
1.14.14.21 dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2 Rhodococcus erythropolis IGTS8 / ATCC 53968
-
 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.21 Rhodococcus erythropolis A0SWL2 gene dszC
-
1.14.14.21 Rhodococcus erythropolis IGTS8 / ATCC 53968 A0SWL2 gene dszC
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.21 dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2
-
 Rhodococcus erythropolis 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
 ?
1.14.14.21 dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2
-
 Rhodococcus erythropolis IGTS8 / ATCC 53968 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.21 cofactor-requiring dibenzothiophene monooxygenase
-
 Rhodococcus erythropolis
1.14.14.21 dibenzothiophene monooxygenase
-
 Rhodococcus erythropolis
1.14.14.21 dszC
-
 Rhodococcus erythropolis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.14.14.21 37
-
 assay at Rhodococcus erythropolis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.14.21 7
-
 assay at Rhodococcus erythropolis

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.21 FMNH2
-
 Rhodococcus erythropolis
1.14.14.21 additional information the enzyme requires NADH, FMNH2, oxygen, and the aid of NADH-FMN oxidoreductase to catalyze the conversion of dibenzothiophene Rhodococcus erythropolis
1.14.14.21 NADH
-
 Rhodococcus erythropolis