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Literature summary extracted from

  • Cao, X.; Cronan, J.E.
    The Streptomyces coelicolor lipoate-protein ligase is a circularly permuted version of the Escherichia coli enzyme composed of discrete interacting domains (2015), J. Biol. Chem., 290, 7280-7290.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.1.20 expressed in an Escherichia coli ligase-deficient strain QC146 Streptomyces coelicolor

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.1.20 40000
-
 x * 40000, SDS-PAGE Streptomyces coelicolor

Organism

EC Number Organism UniProt Comment Textmining
6.3.1.20 Streptomyces coelicolor
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.1.20 ATP + (R)-lipoate
-
 Streptomyces coelicolor lipoyl-AMP + diphosphate
-
 r
6.3.1.20 lipoyl-AMP + [glycine cleavage H protein]-L-lysine
-
 Streptomyces coelicolor [glycine cleavage H protein]-N6-(lipoyl)lysine + AMP
-
 ir
6.3.1.20 lipoyl-AMP + [lE2p subunit of the pyruvate dehydrogenase complex]-L-lysine
-
 Streptomyces coelicolor [E2p subunit of the pyruvate dehydrogenase complex]-N6-(lipoyl)lysine + AMP
-
 ir

Subunits

EC Number Subunits Comment Organism
6.3.1.20 ? x * 40000, SDS-PAGE Streptomyces coelicolor

Synonyms

EC Number Synonyms Comment Organism
6.3.1.20 lipoate ligase
-
 Streptomyces coelicolor
6.3.1.20 LPLA
-
 Streptomyces coelicolor