Data extracted from this reference:
Inhibitors
2.4.2.12
FK866
specific and potent inhibitor
Homo sapiens
Natural Substrates/ Products (Substrates)
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
Homo sapiens
nicotinamide D-ribonucleotide + diphosphate
?
Organism
2.4.2.12
Homo sapiens
P43490
Source Tissue
2.4.2.12
A-2780 cell
Homo sapiens
2.4.2.12
BxPC-3 cell
Homo sapiens
2.4.2.12
culture condition:McCoys 5A medium-grown cell
Homo sapiens
2.4.2.12
DLD-1 cell
Homo sapiens
2.4.2.12
HCC-1937 cell
Homo sapiens
2.4.2.12
HCT-116 cell
Homo sapiens
2.4.2.12
HT-29 cell
Homo sapiens
2.4.2.12
MDA-MB-231 cell
Homo sapiens
2.4.2.12
MDA-MB-468 cell
Homo sapiens
2.4.2.12
SUM-149 cell
Homo sapiens
2.4.2.12
SW-480 cell
Homo sapiens
2.4.2.12
U-87MG cell
Homo sapiens
Substrates and Products (Substrate)
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
736436
Homo sapiens
nicotinamide D-ribonucleotide + diphosphate
?
Synonyms
2.4.2.12
Nampt
Homo sapiens
Inhibitors (protein specific)
2.4.2.12
FK866
specific and potent inhibitor
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
Homo sapiens
nicotinamide D-ribonucleotide + diphosphate
?
Source Tissue (protein specific)
2.4.2.12
A-2780 cell
Homo sapiens
2.4.2.12
BxPC-3 cell
Homo sapiens
2.4.2.12
culture condition:McCoys 5A medium-grown cell
Homo sapiens
2.4.2.12
DLD-1 cell
Homo sapiens
2.4.2.12
HCC-1937 cell
Homo sapiens
2.4.2.12
HCT-116 cell
Homo sapiens
2.4.2.12
HT-29 cell
Homo sapiens
2.4.2.12
MDA-MB-231 cell
Homo sapiens
2.4.2.12
MDA-MB-468 cell
Homo sapiens
2.4.2.12
SUM-149 cell
Homo sapiens
2.4.2.12
SW-480 cell
Homo sapiens
2.4.2.12
U-87MG cell
Homo sapiens
Substrates and Products (Substrate) (protein specific)
2.4.2.12
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
736436
Homo sapiens
nicotinamide D-ribonucleotide + diphosphate
?
General Information
2.4.2.12
malfunction
enzyme inhibition is responsible for ATP depletion, metabolic perturbation, and subsequent tumor growth inhibition
Homo sapiens
2.4.2.12
physiological function
the enzyme catalyzes the first rate-limiting step in converting nicotinamide to NAD+, essential for cellular metabolism, energy production, and DNA repair
Homo sapiens
General Information (protein specific)
2.4.2.12
malfunction
enzyme inhibition is responsible for ATP depletion, metabolic perturbation, and subsequent tumor growth inhibition
Homo sapiens
2.4.2.12
physiological function
the enzyme catalyzes the first rate-limiting step in converting nicotinamide to NAD+, essential for cellular metabolism, energy production, and DNA repair
Homo sapiens