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Literature summary extracted from

  • Oh, H.; Park, Y.; Park, C.
    A mutated PtsG, the glucose transporter, allows uptake of D-ribose (1999), J. Biol. Chem., 274, 14006-14011.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.199 F37Y the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose Escherichia coli
2.7.1.199 G176D the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose Escherichia coli
2.7.1.199 G281D the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose Escherichia coli
2.7.1.199 I283T the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose Escherichia coli
2.7.1.199 L289Q the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1] Escherichia coli
-
 [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.199 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.199 additional information the wild type enzyme does not transport D-ribose Escherichia coli ?
-
 ?
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1]
-
 Escherichia coli [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.199 glucose-specific transporter of phosphoenolpyruvate:carbohydrate phosphotransferase system
-
 Escherichia coli
2.7.1.199 IIBCGlc
-
 Escherichia coli
2.7.1.199 PtsG
-
 Escherichia coli