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Literature summary extracted from

  • Li, H.; Cong, Y.; Lin, J.; Chang, Y.
    Enhanced tolerance and accumulation of heavy metal ions by engineered Escherichia coli expressing Pyrus calleryana phytochelatin synthase (2015), J. Basic Microbiol., 55, 398-405.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.2.15 expressed in Escherichia coli Rosetta (DE3) cells Pyrus calleryana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.15 glutathione + [Glu(-Cys)]n-Gly Pyrus calleryana
-
 Gly + [Glu(-Cys)]n+1-Gly
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.15 Pyrus calleryana
-
 bean pear
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.15 glutathione + [Glu(-Cys)]n-Gly
-
 Pyrus calleryana Gly + [Glu(-Cys)]n+1-Gly
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.15 glutathione gamma-glutamylcysteinyltransferase
-
 Pyrus calleryana
2.3.2.15 PCS1
-
 Pyrus calleryana
2.3.2.15 phytochelatin synthase
-
 Pyrus calleryana

Expression

EC Number Organism Comment Expression
2.3.2.15 Pyrus calleryana enzyme expression is induced after cadmium and copper treatments up

General Information

EC Number General Information Comment Organism
2.3.2.15 physiological function the enzyme has a major role in the detoxification of heavy metals. Escherichia coli with overexpressed phytochelatin synthase 1 has enhanced tolerance to cadmium, copper, sodium, and mercury Pyrus calleryana