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Literature summary extracted from

  • Zhang, Z.; Aboulwafa, M.; Smith, M.; Saier Jr., M.
    The ascorbate transporter of Escherichia coli (2003), J. Bacteriol., 185, 2243-2250.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.194 2,5-diketogulonate less than 15% inhibition at 0.5 mM Escherichia coli
2.7.1.194 2-ketogulonate less than 15% inhibition at 0.5 mM Escherichia coli
2.7.1.194 D-arabitol 34% inhibition at 0.5 mM Escherichia coli
2.7.1.194 L-ascorbate 72% inhibition at 0.5 mM Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.194 0.009
-
 L-ascorbate[side 1] at pH 7.0 and 37°C Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.194 additional information Escherichia coli the sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system, respectively. All three proteins as well as the energy-coupling phosphotransferase system proteins, enzyme I and HPr, are required for the anaerobic utilization and uptake of L-ascorbate in vivo and its phosphoenolpyruvatedependent phosphorylation in vitro ?
-
 ?
2.7.1.194 additional information Escherichia coli BW25113 the sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system, respectively. All three proteins as well as the energy-coupling phosphotransferase system proteins, enzyme I and HPr, are required for the anaerobic utilization and uptake of L-ascorbate in vivo and its phosphoenolpyruvatedependent phosphorylation in vitro ?
-
 ?
2.7.1.194 [protein]-Npi-phospho-L-histidine + L-ascorbate[side 1] Escherichia coli the L-ascorbate transporter is highly specific for L-ascorbate [protein]-L-histidine + L-ascorbate 6-phosphate[side 2]
-
 ?
2.7.1.194 [protein]-Npi-phospho-L-histidine + L-ascorbate[side 1] Escherichia coli BW25113 the L-ascorbate transporter is highly specific for L-ascorbate [protein]-L-histidine + L-ascorbate 6-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.194 Escherichia coli
-
-
-
2.7.1.194 Escherichia coli BW25113
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.194 additional information the sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system, respectively. All three proteins as well as the energy-coupling phosphotransferase system proteins, enzyme I and HPr, are required for the anaerobic utilization and uptake of L-ascorbate in vivo and its phosphoenolpyruvatedependent phosphorylation in vitro Escherichia coli ?
-
 ?
2.7.1.194 additional information the sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system, respectively. All three proteins as well as the energy-coupling phosphotransferase system proteins, enzyme I and HPr, are required for the anaerobic utilization and uptake of L-ascorbate in vivo and its phosphoenolpyruvatedependent phosphorylation in vitro Escherichia coli BW25113 ?
-
 ?
2.7.1.194 [protein]-Npi-phospho-L-histidine + L-ascorbate[side 1] the L-ascorbate transporter is highly specific for L-ascorbate Escherichia coli [protein]-L-histidine + L-ascorbate 6-phosphate[side 2]
-
 ?
2.7.1.194 [protein]-Npi-phospho-L-histidine + L-ascorbate[side 1] the L-ascorbate transporter is highly specific for L-ascorbate Escherichia coli BW25113 [protein]-L-histidine + L-ascorbate 6-phosphate[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.194 L-ascorbate transporter
-
 Escherichia coli
2.7.1.194 SGAT
-
 Escherichia coli
2.7.1.194 sgaTBA operon name Escherichia coli
2.7.1.194 SgaTBA PTS permease
-
 Escherichia coli