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Literature summary extracted from

  • Wu, M.C.; Chen, Y.C.; Lin, T.L.; Hsieh, P.F.; Wang, J.T.
    Cellobiose-specific phosphotransferase system of Klebsiella pneumoniae and its importance in biofilm formation and virulence (2012), Infect. Immun., 80, 2464-2472.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.205 membrane
-
Klebsiella pneumoniae 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.205 [protein]-Npi-phospho-L-histidine + D-cellobiose[side 1] Klebsiella pneumoniae
-
[protein]-L-histidine + D-cellobiose 6'-phosphate[side 2]
-
?
2.7.1.205 [protein]-Npi-phospho-L-histidine + D-cellobiose[side 1] Klebsiella pneumoniae NTUH-K2044
-
[protein]-L-histidine + D-cellobiose 6'-phosphate[side 2]
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.205 Klebsiella pneumoniae
-
-
-
2.7.1.205 Klebsiella pneumoniae NTUH-K2044
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.205 [protein]-Npi-phospho-L-histidine + D-cellobiose[side 1]
-
Klebsiella pneumoniae [protein]-L-histidine + D-cellobiose 6'-phosphate[side 2]
-
?
2.7.1.205 [protein]-Npi-phospho-L-histidine + D-cellobiose[side 1]
-
Klebsiella pneumoniae NTUH-K2044 [protein]-L-histidine + D-cellobiose 6'-phosphate[side 2]
-
?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.205 cellobiose-specific phosphotransferase system
-
Klebsiella pneumoniae
2.7.1.205 EIIC cellobiose-specific subunit IIC of enzyme II Klebsiella pneumoniae

General Information

EC Number General Information Comment Organism
2.7.1.205 malfunction enzyme deletion mutants exhibit reduced virulence Klebsiella pneumoniae
2.7.1.205 physiological function the enzyme is responsible for biofilm formation and contributes to virulence Klebsiella pneumoniae