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Literature summary extracted from

  • Gandia, M.; Harries, E.; Marcos, J.F.
    The myosin motor domain-containing chitin synthase PdChsVII is required for development, cell wall integrity and virulence in the citrus postharvest pathogen Penicillium digitatum (2014), Fungal Genet. Biol., 67, 58-70.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.16 gene chsVII, phylogenetic analysis, quantitative RT-PCR enzyme expression analyis Penicillium digitatum

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.16 additional information disruption of the gene coding PdChsVII, which contains a short version of a myosin motor domain, has been achieved by using Agrobacterium tumefaciens strain AGL-1-mediated transformation, morphological changes and chitin content in Penicillium digitatum PdchsVII disruption strains, overview Penicillium digitatum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n Penicillium digitatum
-
 UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n Penicillium digitatum CECT 20796
-
 UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Penicillium digitatum R4I3H8 isolate PHI26, gene chsVII
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2.4.1.16 Penicillium digitatum CECT 20796 R4I3H8 isolate PHI26, gene chsVII
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.16 additional information growth and conidia production of wild-type and disruption mutant strains, and relative expression of chs genes in Penicillium digitatum strain CECT20796 under different growth conditions, overview Penicillium digitatum
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2.4.1.16 mycelium
-
 Penicillium digitatum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Penicillium digitatum UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-alpha-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Penicillium digitatum CECT 20796 UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.16 More domain structure of PdChsVII Penicillium digitatum

Synonyms

EC Number Synonyms Comment Organism
2.4.1.16 PdChsVII
-
 Penicillium digitatum

General Information

EC Number General Information Comment Organism
2.4.1.16 evolution chitin synthase genes (chs) constitute a complex family in filamentous fungi and are involved in fungal development, morphogenesis, pathogenesis and virulence, phylogenetic analysis of chsI-VII Penicillium digitatum
2.4.1.16 malfunction PdchsVII mutants have reduced virulence on citrus fruit. Disruption of gene chsVII has an effect on the expression of other isozymes during growth in liquid PDB medium. The largest increase of expression is shown in both disruption mutant strains PDMG672 and PDMG439 by gene PdchsII, which is induced up to 50fold during growth, while in strain CECT20796 it remains almost constant or even declines. Expression of PdchsIV, PdchsV and PdchsVI genes is also induced in disruption mutants compared to the parental strain. Expression of PdchsI and PdchsIII remaines at similar levels in the mutant and wild-type strains Penicillium digitatum
2.4.1.16 physiological function chitin synthase PdChsVII is required for development, cell wall integrity and virulence in the citrus postharvest pathogen Penicillium digitatum. Differential expression of chitin synthase genes in PdchsVII mutants in response to infection Penicillium digitatum