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Literature summary extracted from

  • Dziewit, L.; Pyzik, A.; Romaniuk, K.; Sobczak, A.; Szczesny, P.; Lipinski, L.; Bartosik, D.; Drewniak, L.
    Novel molecular markers for the detection of methanogens and phylogenetic analyses of methanogenic communities (2015), Front. Microbiol., 6, 694.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.247 gene mtbA, DNA and amino acid sequence determination and analysis, development and optimization of specific detection primers, phylogenetic analysis and tree Methanosarcina barkeri
2.1.1.247 gene mtbA, DNA and amino acid sequence determination and analysis, development and optimization of specific detection primers, phylogenetic analysis and tree Methanomethylovorans hollandica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.247 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + coenzyme M Methanosarcina barkeri
-
 methyl-CoM + a [Co(I) dimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + coenzyme M Methanomethylovorans hollandica
-
 methyl-CoM + a [Co(I) dimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M Methanosarcina barkeri
-
 methyl-CoM + a [Co(I) methylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M Methanomethylovorans hollandica
-
 methyl-CoM + a [Co(I) methylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) trimethylamine-specific corrinoid protein] + coenzyme M Methanosarcina barkeri
-
 methyl-CoM + a [Co(I) trimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) trimethylamine-specific corrinoid protein] + coenzyme M Methanomethylovorans hollandica
-
 methyl-CoM + a [Co(I) trimethylamine-specific corrinoid protein]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.247 Methanomethylovorans hollandica
-
 sample of microbial consortium involved in biogas production collected from an effluent sludge tank from a one-stage wastewater treatment plant anaerobic digester at MPWIK Pulawy, Poland, gene mtbA
-
2.1.1.247 Methanosarcina barkeri O30640 sample of microbial consortium involved in biogas production collected from the fermenter tank of an agricultural two-stage biogas plant anaerobic digester in Miedzyrzec Podlaski, Poland, gene mtbA
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.247 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + coenzyme M
-
 Methanosarcina barkeri methyl-CoM + a [Co(I) dimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) dimethylamine-specific corrinoid protein] + coenzyme M
-
 Methanomethylovorans hollandica methyl-CoM + a [Co(I) dimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M
-
 Methanosarcina barkeri methyl-CoM + a [Co(I) methylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M
-
 Methanomethylovorans hollandica methyl-CoM + a [Co(I) methylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) trimethylamine-specific corrinoid protein] + coenzyme M
-
 Methanosarcina barkeri methyl-CoM + a [Co(I) trimethylamine-specific corrinoid protein]
-
 ?
2.1.1.247 a [methyl-Co(III) trimethylamine-specific corrinoid protein] + coenzyme M
-
 Methanomethylovorans hollandica methyl-CoM + a [Co(I) trimethylamine-specific corrinoid protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.247 methylated MtmC protein:CoM methyltransferase
-
 Methanosarcina barkeri
2.1.1.247 methylated MtmC protein:CoM methyltransferase
-
 Methanomethylovorans hollandica
2.1.1.247 methylated [methylamine-specific corrinoid protein]:coenzymeM methyltransferase
-
 Methanosarcina barkeri
2.1.1.247 methylated [methylamine-specific corrinoid protein]:coenzymeM methyltransferase
-
 Methanomethylovorans hollandica

General Information

EC Number General Information Comment Organism
2.1.1.247 evolution Methanosarcinales are mainly responsible for the utilization of methylamines. mtbA-Specific primers LMTBA/RMTBA-detected sequences from analyzed samples mostly belong to the Methanosarcinales, with two dominating species: Methanosarcina barkeri and Methanomethylovorans hollandica Methanosarcina barkeri
2.1.1.247 evolution Methanosarcinales are mainly responsible for the utilization of methylamines. mtbA-Specific primers LMTBA/RMTBA-detected sequences from analyzed samples mostly belong to the Methanosarcinales, with two dominating species: Methanosarcina barkeri and Methanomethylovorans hollandica Methanomethylovorans hollandica
2.1.1.247 metabolism the enzyme is involved in the conversion of methylated amines into methyl-CoM, part of the superpathway of methanogenesis, overview Methanosarcina barkeri
2.1.1.247 metabolism the enzyme is involved in the conversion of methylated amines into methyl-CoM, part of the superpathway of methanogenesis, overview Methanomethylovorans hollandica