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Literature summary extracted from

  • Deng, Z.J.; Butcher, N.J.; Mortimer, G.M.; Jia, Z.; Monteiro, M.J.; Martin, D.J.; Minchin, R.F.
    Interaction of human arylamine N-acetyltransferase 1 with different nanomaterials (2014), Drug Metab. Dispos., 42, 377-383.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.5 thermo-responsive diblock copolymer nanoparticle
-
 Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.5
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.5 additional information the enzyme is inhibited by layered silicate nanoparticles and layered double hydroxide clays Homo sapiens
2.3.1.5 SiO2
-
 Homo sapiens
2.3.1.5 TiO2
-
 Homo sapiens
2.3.1.5 ZnO
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.5 0.106
-
 4-Aminobenzoate at pH 7.4 and 37°C Homo sapiens
2.3.1.5 0.438
-
 acetyl-CoA at pH 7.4 and 37°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.5 cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.5 33000
-
 x * 33000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.5
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 acetyl-CoA + 4-aminobenzoate
-
 Homo sapiens CoA + N-acetyl-4-aminobenzoate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.5 ? x * 33000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.3.1.5 arylamine-N-acetyltransferase 1
-
 Homo sapiens
2.3.1.5 NAT1
-
 Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.1.5 37 47 NAT1 is sensitive to heat denaturation and shows a significant loss in activity as temperature is increased from 37°C to 47°C Homo sapiens