Literature summary extracted from

Li, W.; Gigante, A.; Perez-Perez, M.J.; Yue, H.; Hirano, M.; McIntyre, T.M.; Silverstein, R.L.
Thymidine phosphorylase participates in platelet signaling and promotes thrombosis (2014), Circ. Res., 115, 997-1006.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.4.2.4	50000	-	x * 50000, SDS-PAGE	Mus musculus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.2.4	thymidine + phosphate	Mus musculus	-	thymine + 2-deoxy-alpha-D-ribose 1-phosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.4	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.2.4	blood platelet	-	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.4	thymidine + phosphate	-	Mus musculus	thymine + 2-deoxy-alpha-D-ribose 1-phosphate	-	?

Subunits

EC Number	Subunits	Comment	Organism
2.4.2.4	?	x * 50000, SDS-PAGE	Mus musculus

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.4	TYMP	-	Mus musculus

General Information

EC Number	General Information	Comment	Organism
2.4.2.4	malfunction	collagen-, collagen-related peptide-, adenosine diphosphate-and/or thrombin-induced platelet aggregation are significantly attenuated in enzyme deficient platelets. Tymp deficiency also significantly decreases agonist-induced P-select in expression	Mus musculus
2.4.2.4	physiological function	the enzyme participates in platelet signaling and promotes thrombosis by platelet activation	Mus musculus

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Release 2023.1 (January 2023)