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Literature summary extracted from

  • Sindhuwinata, N.; Grimm, L.L.; Weissbach, S.; Zinn, S.; Munoz, E.; Palcic, M.M.; Peters, T.
    Thermodynamic signature of substrates and substrate analogs binding to human blood group B galactosyltransferase from isothermal titration calorimetry experiments (2013), Biopolymers, 99, 784-795.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.37 expressed in Escherichia coli BL21 cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.37 2-amino-2-deoxy-D-galactosamine
-
 Homo sapiens
2.4.1.37 alpha-L-Fuc-(1,2)-beta-D-3-amino-3-deoxy-Gal-O-octyl
-
 Homo sapiens
2.4.1.37 alpha-L-Fucp-(1,2)-beta-D-(3-amino-3-deoxy)-Galp-O-(CH2)7-CH3
-
 Homo sapiens
2.4.1.37 beta-D-(3-amino-3-desoxy)-Galp-O-(CH2)7-CH3
-
 Homo sapiens
2.4.1.37 additional information not inhibited by ethanolamine, 2-amino-2-deoxy glucosamine, and 2-amino-2-deoxy-mannosamine Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.37 UDP-alpha-D-galactose + alpha-L-fucosyl-(1,2)-D-galactosyl-R Homo sapiens
-
 UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactosyl-R
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.37 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.37
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.37 UDP-alpha-D-galactose + alpha-L-fucosyl-(1,2)-D-galactosyl-R
-
 Homo sapiens UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactosyl-R
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.37 blood group B galactosyltransferase
-
 Homo sapiens
2.4.1.37 GTB
-
 Homo sapiens