EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.65 | ADP | about 30% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | dGDP | about 40% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | dGDP | about 76% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | GDP | about 78% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | GDP | about 80% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | GDP-6-amino-beta-L-fucose | about 45% inhibition at 1 mM | Helicobacter pylori | |
2.4.1.65 | GDP-6-amino-beta-L-fucose | 78% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | GTP | about 70% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | GTP | about 80% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | IDP | about 60% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | IDP | about 30% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | L-fucose | about 20% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | additional information | not inhibited by GMP | Helicobacter pylori | |
2.4.1.65 | additional information | not inhibited by L-fucose, GMP and ADP | Homo sapiens | |
2.4.1.65 | [1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 70% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | [1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosinediphosphate | about 74% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | [1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | about 76% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | [1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | about 73% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | [1-(beta-D-lactosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 60% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | [1-(beta-D-lactosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 45% inhibition at 0.4 mM | Homo sapiens | |
2.4.1.65 | [1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 58% inhibition at 0.4 mM | Helicobacter pylori | |
2.4.1.65 | [1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 60% inhibition at 0.4 mM | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.65 | Helicobacter pylori | - |
- |
- |
2.4.1.65 | Homo sapiens | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.65 | alpha1,3-fucosyltransferase | - |
Helicobacter pylori |
2.4.1.65 | alpha1,3-fucosyltransferase IX | - |
Homo sapiens |
2.4.1.65 | FucT | - |
Helicobacter pylori |
2.4.1.65 | FucT IX | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.65 | 0.0503 | - |
dGDP | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.0779 | - |
GDP | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.0807 | - |
GTP | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.102 | - |
GDP-6-amino-beta-L-fucose | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.137 | - |
[1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.186 | - |
[1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens | |
2.4.1.65 | 0.19 | - |
[1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.4.1.65 | 0.049 | - |
at pH 4.5 and 37°C | Homo sapiens | dGDP | |
2.4.1.65 | 0.059 | - |
at pH 4.5 and 37°C | Homo sapiens | GDP | |
2.4.1.65 | 0.094 | - |
at pH 4.5 and 37°C | Homo sapiens | GTP | |
2.4.1.65 | 0.104 | - |
at pH 4.5 and 37°C | Homo sapiens | GDP-6-amino-beta-L-fucose | |
2.4.1.65 | 0.134 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | |
2.4.1.65 | 0.139 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | |
2.4.1.65 | 0.247 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate |