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Literature summary extracted from

  • Huma, T.; Maryam, A.; Qamar, T.U.
    Molecular modeling and docking of wheat hydroquinone glucosyl transferase by using hydroquinone, phenyl phosphorodiamate and n-(n butyl) phosphorothiocic triamide as inhibitors (2014), Bioinformation, 10, 124-129.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.218 hydroquinone Glu274 is acting as an acidic backbone acceptor residue. Lys262, a basic amino acid from the active site of wheat Hydroquinone glucosyltransferase interacts with the hydroxyl group of hydroquinone and behaves as a side chain donor molecule. Asp264 is also observed as an interacting residue from the active site of hydroquinone glucosyltransferase. It binds to the hydroxyl group of hydroquinone inhibitor and donates hydrogen ion from its side chain group Triticum aestivum
2.4.1.218 additional information enzyme molecular docking of urease inhibitors hydroquinone, phenyl phosphorodiamate, and N-(n-butyl) phosphorothiocic triamide, three-dimensional structure analysis using homology modeling, and interactions analysis, overview Triticum aestivum
2.4.1.218 N-(n-butyl) phosphorothiocic triamide Glu274 is acting as an acidic backbone donor residue and interacts with the amino group of the inhibitor Triticum aestivum
2.4.1.218 phenyl phosphorodiamate Glu395 is directly interacting with amino group of the inhibitor Triticum aestivum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.218 Ni2+ required, metalloenzyme Triticum aestivum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.218 UDP-glucose + hydroquinone Triticum aestivum
-
 UDP + hydroquinone-O-beta-D-glucopyranoside
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.218 Triticum aestivum D8LAL9
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.218 UDP-glucose + hydroquinone
-
 Triticum aestivum UDP + hydroquinone-O-beta-D-glucopyranoside
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.218 hydroquinone glucosyl transferase
-
 Triticum aestivum