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Literature summary extracted from

  • Lee, C.G.; Park, J.K.
    Comparison of inhibitory activity of bioactive molecules on the dextransucrase from Streptococcus mutans (2015), Appl. Microbiol. Biotechnol., 99, 7495-7503.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.5 alginate 80% activation Streptococcus mutans
2.4.1.5 D-galactose 30% activation at 1%, with concentration of 1% sucrose Streptococcus mutans
2.4.1.5 D-mannose 40% activation at 1%, with concentration of 1% sucrose Streptococcus mutans
2.4.1.5 fucoidan 20% activation Streptococcus mutans
2.4.1.5 lactose 50% activation at 1%, with concentration of 1% sucrose Streptococcus mutans
2.4.1.5 additional information water-soluble extract of Artemisia annua , 2.5fold enzyme activation Streptococcus mutans
2.4.1.5 additional information water-soluble extract of Artemisia sajaval , 3fold enzyme activation Streptococcus mutans

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.5 beta-Glucan slight inhibition Streptococcus mutans
2.4.1.5 chitosan various sizes of chitosans (CTSN, CTSN-P, CTSN-B, and CTSN-S) prepared as low molecular weight chitosan show significant inhibitory effect on enzyme DSase activity, antimicrobial activity of CTSNs toward Streptococcus mutans, overview Streptococcus mutans
2.4.1.5 D-galactosamine complete inhibition at 1% versus 1% sucrose Streptococcus mutans
2.4.1.5 D-glucosamine complete inhibition at 1% versus 1% sucrose Streptococcus mutans
2.4.1.5 D-mannosamine complete inhibition at 1% versus 1% sucrose Streptococcus mutans
2.4.1.5 D-xylose about 40% inhibition at 1% versus 1% sucrose Streptococcus mutans
2.4.1.5 hyaluronic acid molecular weight of about 8.9 kDa Streptococcus mutans
2.4.1.5 additional information D-glucose has no effect on enzyme ativity; water-soluble extract of Curcuma sp., strong enzyme inhibition Streptococcus mutans
2.4.1.5 sulfated chitin
-
 Streptococcus mutans

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.5 Streptococcus mutans
-
-
-
2.4.1.5 Streptococcus mutans ATCC 700610 / UA159
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.4.1.5 DSase
-
 Streptococcus mutans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.5 4.5 7 assay at Streptococcus mutans