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Literature summary extracted from

  • Hada, T.; Yamamoto, T.; Yamamoto, A.; Ohkura, K.; Yamazaki, N.; Takiguchi, Y.; Shinohara, Y.
    Comparison of the catalytic activities of three isozymes of carnitine palmitoyltransferase 1 expressed in COS7 cells (2014), Appl. Biochem. Biotechnol., 172, 1486-1496.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.21 expressed in Escherichia coli and COS-7 cells Rattus norvegicus

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.21 A587S/S588A/M592L/R594L inert isoform CPT1c Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 0.24
-
 L-carnitine isoform CPT1c, at pH 7.4 and 30°C Rattus norvegicus
2.3.1.21 4.44
-
 L-carnitine isoform CPT1b, at pH 7.4 and 30°C Rattus norvegicus
2.3.1.21 11.1
-
 L-carnitine isoform CPT1a, at pH 7.4 and 30°C Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 90200
-
 x * 90200, estimated from SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-palmitoylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 additional information isozyme CPT1c is inert Rattus norvegicus ?
-
 ?
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.21 ? x * 90200, estimated from SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 carnitine palmitoyltransferase 1
-
 Rattus norvegicus
2.3.1.21 CPT1A isoform Rattus norvegicus
2.3.1.21 CPT1B isoform Rattus norvegicus
2.3.1.21 CPT1c isoform Rattus norvegicus