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Literature summary extracted from

  • Kubicek-Sutherland, J.; Heithoff, D.; Ersoy, S.; Shimp, W.; Mahan, M.
    Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes (2014), Vaccine, 32, 1451-1459.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine Yersinia pseudotuberculosis
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 S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.72 Yersinia pseudotuberculosis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine
-
 Yersinia pseudotuberculosis S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.72 Dam
-
 Yersinia pseudotuberculosis
2.1.1.72 DNA adenine methyltransferase
-
 Yersinia pseudotuberculosis

General Information

EC Number General Information Comment Organism
2.1.1.72 physiological function the enzyme is essential for cell viability and confers potent cross-protective efficacy as well as decreased virulence and spontaneous mutation frequency Yersinia pseudotuberculosis